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Flashcards in Schizophrenia and Other Psychotic Disorders Deck (17)
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1

Schizophrenia prognostic variables

1% of population

Positive symptoms - less ominious
Negative symptoms - poor prognosis (along with poor cognitive performance, poor support, younger onset, insidious onset, premorbid-schizoid,schizotypal, few friends, minimal social activities)

2

Precipitating events in schizophrenia

psychosocial stressors, traumatic events, drug and alcohol abuse, (cannabis incr. 6x risk)

3

MoA of schizophrenia

Increased dopamine in neuronal tracts, blocking pathways.
Increased 5HT, NE.
Decreased GABA and glutamate.

4

Features of schizophrenia: describe.
-Form of thought - loosening associations, poverty of content and speech, thought blocking (talk nonstop and then STOP)
-Content of thought - delusions
-Perceptual disorders - hallucinations (what type?)
-Affect

loosening of associations - connections among ideas are absent/obscure
hallucinations - auditory or visual
affect - blunted/flat/inappropriate

5

describe four positive symptoms associated with schizophrenia

delusions, hallucinations, catatonia, agitation

6

describe four negative symptoms associated with schizophrenia

affective flattening, apathy, social withdrawl, anhedonia, pverty of thought, content of speech

7

Describe DSM5 dx of schizophrenia

**Time frame?

2 or more sx for most of 1 mon5h of: delusions, hallucinations, disorganzied speech, grossly disorganized or catatonic behavior, negative symptoms. **Duration of at least 6mo of persistent symptoms.

8

What three actions should be taken in a hospital if a schizophrenic is violent/has hx of violent acts.

RESTRAINTS, then IM lorazepam or haloperidol (anti psychotics)

9

What drug reduces suicidal ideations?
AE

clozapine

AE - agranulocytosis

10

Weight gain due to what anti-psychotic drugs?

~pines - olanzapine, quetiapine

11

AE of ant-psychotic ziprasidone

AT prolongation

12

What is this: uninterrupted period of illness with either a major depressive episode or manic episode concurrent with symptoms that meet criterion A for schizophrenia. Same period of illness, have been delusions or hallucinations for at least 2 weeks in absence of prominent mood symptoms.

schizoaffective disorder

13

What is this:
duration of an episode (delusions, hallucinations, disorganzied speech, grozzly disorganized or catatonic behavior) at least 1 day and no more than 1 month, with eventual return to premorbid level of functioning.

Brief psychotic disorder

***Less than 1mo

14

What meets criteria for schizophrenia, but lasts **between 1-6 months**?

schizophreniform

15

What is the time frame for delusional disorder?

at least 1 mo

16

time frames for:
schizophrenia
schizophreniform
brief psychotic disorder

schizophrenia - >6mo
schizophreniform 1-6mo
brief psychotic disorder less than 1mo

17

What are each of these:
-Very introverted and voluntarily withdraws from social interactions
-Schizoid symptoms + magical thinking + odd behavior
-Schizotypal + psychosis
-Schizophrenia + mood disorder

-schizoid
-schizotypal
-schizophrenia
-schizoaffective