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Flashcards in Substance Abuse Deck (16)
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1

**Give what for alcohol withdrawal?

Benzo (GABA agonist to decr seizure), anticonvulsant (reduce SZ risk), thiamine supplememntation

2

disulfram (Alc Dehydr inhibitor)
naltrexone (opioid antag)
acamprosate (check renal fxn bc cleared renally)

- all are given for what?

for alcohol (to stop from drinking)

3

naltrexone (opioid antag)
buprenorphine (PARTIAL mu agon)
methadone (mu agon)

- all are given for what?

which has ceiling effect?

opioid use disorder treatment

buprenorphine has ceiling effect

4

tobacco ad drug interactions

CYP1A2 inhibitor (i.e. olanzapine)

5

what category is MDMA?

a hallucinogen

6

neuroadaptation -
MDMA

MDMA - 5HT2 receptor agonists

7

nystagmus

PCP

8

pinpoint pupils

opioids

9

neuroadaptation of ____ drug:
opiate receptor effects. allosteric modulator of glutamate NMDA receptor

PCP

10

neuroadaptation of ____ drug:
increased DA and decreased NE

opioids

11

neuroadaptation of ____ drug:
it mainly prevents reuptake of DA

cocaine

12

neuroadaptation of ____ drug:
inhibit reuptake of DA, NE, SE - greatest effect on DA

amphetamines

13

neuroadaptation of ____ drug:
nAChR on DA neurons in VTA release DA in NAc

tobacco

14

neuroadaptation of ____ drug:
5HT, DA, NE but predominantly 5HT2 receptor agonists

MDMA

15

neuroadaptation of ____ drug:
CB1, CB2 cannabinoid receptors in brain/body
-coupled G protein and AC to CA channel inhibiting Ca influx

cannabis

16

withdrawal of what class is not life threatening?

opioids