Section 15

Question 1

most important factor contributing to patient mortality in TCA toxicity

Answer 1

Cyclic antidepressant–induced cardiotoxicity

Question 2

most frequent dysrhythmia noted in cyclic antidepressant toxicity; bupropion; SNRI; MAOI

Answer 2

Sinus tachycardia

Question 3

most common symptom reported after cyclic antidepressant exposure

Answer 3

Altered mental status

Question 4

most potent sodium channel blocker among the cyclic antidepressants

Answer 4

desipramine

Question 5

most frequently reported cardiovascular abnormality in trazodone

Answer 5

Orthostatic hypotension

Question 6

most common ECG abnormality in trazodone

Answer 6

moderate prolongation of the QT interval

Question 7

Most common form of pharmacotherapy for depression

Answer 7

SSRIs

Question 8

associated with the highest incidence of seizures among the SSRIs.

Answer 8

Citalopram

Question 9

most serious drug-related adverse effect of SSRI psychopharmacotherapy

Answer 9

Serotonin syndrome

Question 10

drug class most commonly associated with serotonin syndrome.

Answer 10

antidepressant

Question 11

most common cause of death in serotonin syndrome

Answer 11

severe hyperthermia

Question 12

Most common cardiovascular manifestations of antipsychotic overdose

Answer 12

tachycardia and orthostatis hypotension

Question 13

antipsychotics with highest rate of QT prolongation

Answer 13

amisulpride and thioridazine

Question 14

antipsychotics with highest development of type 2 diabetes mellitus and diabetic ketoacidosis

Answer 14

olanzapine

Question 15

most common disorder creating diagnostic confusion is serotonin syndrome

Answer 15

NMS

Question 16

most prevalent endocrine dysfunction of chronic lithium therapy

Answer 16

hypothyroidism

Question 17

most common class of antiepileptic drugs used in developing countries

Answer 17

Barbiturates

Question 18

most common alcohols ingested

Answer 18

Ethanol and isopropanol

Question 19

most frequently used and abused drug in the world.

Answer 19

Ethanol

Question 20

Most frequently cited causes of death of MDMA

Answer 20

hyperthermia and hyponatremia

Question 21

the most common cause of an osmolar gap on serum electrolyte analysis

Answer 21

Ethanol ingestion

Question 22

most commonly sold as raw cactus or “buttons,”

Answer 22

peyote

Question 23

most common agent currently reported in NSAID overdoses

Answer 23

ibuprofen

Question 24

most common in acute overdose in methylxanthine toxicity

Answer 24

Hypokalemia

Question 25

most common cardiac manifestation of both caffeine and theophylline use and toxicity

Answer 25

sinus tachycardia

Question 26

most common effects of nicotine overuse

Answer 26

nausea and vomiting

Question 27

earlies manifestation of Acute digoxin toxicity

Answer 27

Nausea, vomiting, anorexia, and vague abdominal pain

Question 28

Most common arrhythmias in digoxin toxicity

Answer 28

premature ventricular contractions and bradycardic rhythms

Question 29

hallmark of severe toxicity in beta blockers

Answer 29

bradycardia with shock

Question 30

most common physiologic abnormality after overdose of CCB

Answer 30

Hypotension

Question 31

most serious clinical manifestation in overdose in Spironolactone and Eplerenone

Answer 31

Hyperkalemia and hypotension

Question 32

most typical adverse effect observed usually within 30 to 90 minutes after ingestion in doxazosin, prazosin, and terazosin (a1 adrenergic antagonist)

Answer 32

Orthostatic hypotension

Question 33

most commonly used α2-adrenergic agonist; primary indication for rebound hypertension

Answer 33

Clonidine

Question 34

most consequential adverse effect associated with ACEIs and ARBs

Answer 34

angioedema

Question 35

most frequent sign of acute valproic toxicity

Answer 35

CNS depression

Question 36

clinical sign most consistently associated with acute iron toxicity

Answer 36

vomiting

Question 37

most important factor guiding the decision to terminate deferoxamine therapy because measured iron levels are artificially depressed by the presence of deferoxamine and urine color change can be unreliable

Answer 37

clinical recovery of patient

Question 38

Most common radiologic finding in hydrocarbon pulmonary toxicity

Answer 38

bilateral infiltrates at the bases more common to be multilobar and to the right

Question 39

Most worrisome acute complication found in solvent abusers (hydrocarbons) is

Answer 39

sudden sniffing death syndrome

Question 40

Most common household alkali

Answer 40

bleach

Question 41

most common overdose that produces anticholinergic toxicity.

Answer 41

Antihistamine (particularly diphenhydramine) overdose

Question 42

most clinically significant cases of human metal poisoning

Answer 42

Lead and mercury

Question 43

most clinically significant toxic metalloid

Answer 43

Arsenic

Question 44

most common causes of death in arsenic poisoning

Answer 44

Hypotension and dysrhythmias

Question 45

most active form of vitamin D

Answer 45

d-α-tocopherol

Question 46

Most common adverse reaction to macrolide

Answer 46

Gi distress

Question 47

local anesthetic most commonly associated with methemoglobinemia

Answer 47

Benzocaine