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Flashcards in Sepsis Deck (15):
1

WHat is SIRS?

Systemic Inflammatory Response Process

2

What is Sepsis?

SIRS + Infection

3

What qualifies SEVERE Sepsis?

Evidence of organ dysfunction

4

What is Septic Shock?

Sepsis and Hypotension despite adequate fluid resuccitation

5

WHat are the Source Specific clinical Symptoms of Sepsis?
Skin
Resp
GI
GU
Blood Borne

Skin: Erythema, swelling, drainage
Resp: cough, sputum, chest pain
GI: abd discomfort, pain, distention, diarrhea, N/V, jaundice
GU: dysuria, hematuria, flank pain,
BB: Non-specific

6

Who is at risk for sepsis?

DM
Malnutrition
Malignancy
Immunosupression
Chronic Steroids
Immune def
Post Transplant

7

Why is the source/location of the infection important?

Can tell you what kind of bacteria, what Abtx you need to use

8

What labs do you order with suspected Sepsis?

CBC: Leukocytosis or penia
Thrombocytosis or penia
Anemia
Creatine, K+
Bicarb
Lactate
Glycemia
LFT
Coag Profile, PT, PTT, INR
ABG (pH)

9

What makes up SIRS Criteria?
***

Temp >38C(100.4) or 90
RR >20 or PaCO2 12k, 10% bands

10

What is the APACHE II score used for?

Determine risk of mortality in the ICU

11

WHat are the first steps in a Pt with possible sepsis?

IV Site
BP Monitoring
Urinary Cath

12

What is the equation used to calc. MAP?

MAP = (SABP + 2 DABP)/3

13

What is the treatment of choice for fluid therapy?

Crystalloids (Lactated ringers?)
30mL/kg 2 L
1x 16 guage
2x 18 guage

14

What vasopressors are used in Septic Shock?

NE
EPI
Vasopressin

15

What are the guidelines for Antibiotic therapy?

The sooner the better!
Broad spectrum Empiric Abtx within one hour of Hypotension
De-Escalate to more specific therapy ASAP
Monitor Lactate to know if your therapy is working