Session 2 - Acute Inflammation Flashcards Preview

Semester 2 - Mechanisms of Disease > Session 2 - Acute Inflammation > Flashcards

Flashcards in Session 2 - Acute Inflammation Deck (12):
1

Give five causes of acute inflammation

* Microbial infections e.g. pyogenic organisms

* Hypersensitivity reactions

* Physical agents e.g. heat and trauma

* Chemicals

* Tissue necrosis – elicits inflammatory reaction

2

What is the purpose of acute inflammation?

To limit disease process

3

Give the five symptom of acute inflammation

* Rubor – redness

* Tumor – swelling

* Calor – heat

* Dolor – pain

* Loss of sensation

4

Give four microscopic features of acute inflammation

Tissue oedema
Neturophil margination and emigration
Dead myocytes
Neutrophils

5

What is the purpose of oedema? (3)

Delivers plasma proteins to site of injury
Dilutes toxins
Increases lymphatic drainage

6

Give three plasma proteins involved in oedema

Immunoglobulins, inflammatroy mediators, fibrinogen

7

What is the purpose of vasodilation?

Increases delivery and temperature

8

What is the purpose of neutrophil margination and emigration into site of inflammation?

Removes pathogenic organisms and necrotic debris

9

Explain how rubor relates to microscopic changes

Vasodilation

10

How is tumour caused?

Oedema/infiltration of neutrophils

11

How is calor caused?

Vasodilation

12

How is dolor caused?

* Dolor – result of chemical mediators e.g. bradykinin is also involved in the pain mechanism > dolor enforces rest > reduces chance of further traumatic damage