Session 23 - Urinary III Flashcards Preview

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Flashcards in Session 23 - Urinary III Deck (63):
1

What can cause hemoglobinuric nephrosis?

Increased circulating hemoglobin in a hemolytic crissi

2

What can cause hemoglobiuric nephrosis in sheep?

Chronic copper toxicity

3

What can cause hemoglobiuric nephrosis in cattle?

Leptosporosis + Babesiosis

4

What can cause hemogloburic nephrosis in dogs?

Babesiosis + AIHA

5

What can cause hemogloburic nephoris in horses?

Red maple leaf toxicity

6

By what pathologic mechanism does hemogloburic nephoris occur?

Renal ischemia + Increased serum hemoglobin
Passage of hemoglobin through glomeruli
Intratubular casts of hemoglobin pigment
Compounds tubular epithelial damage

7

What is the gross appearance of hemogloburic nephrosis?

Gun-metal blue to chocolate color of kidney

8

What causes myglobinuric nephrosis?

Acute, extensive muscle necrosis

9

What can cause myoglobinuric nephrosis in wildlife?

Capture myopathy

10

What is seen in horses with myoglobinuric nephrosis?

Azoturia
Acute rhabdomyolysis

11

What is another name for acute rhabdomyolysis in horses?

Monday morning disease

12

What is the pathogensis of myoglobinuric nephrosis?

Similar to hemogloburic nephrosis
Myoglobin seen earlier and more readily in urine

13

Why is myoglobin seen quicker then hemoglobin?

Smaller, no carrier protein needed

14

What does lilies cause in cats?

Acute tubular necrosis

15

What is renal papillary necrosis commonly associated with?

Hypoperfusion of the inner medulla

16

What commonly causes renal papillary necrosis in equine?

Phenylbutazone or Flunixin meglumine

17

What commonly causes renal papillary necrosis in dogs and cats

Ibuprofen + Aspirin + Acetominophen

18

By what mechanism does Acetominophen cause renal papillary necrosis?

Directly damages tubular epithelium

19

What can make NSAID toxicity worse?

Dehydration

20

How do NSAIDs cause renal papillary necrosis?

Reduction of prostaglandins which protect the kidney from ischemia

21

What cell type is responsible for prostaglandin release in teh kidney?

Interstitial cells

22

When are uroliths most common in cattle?

Males

23

Where are stones found most commonly in cattle?

Sigmoid flexure of males

24

What can exacerbate the effects of uroliths?

Dehydration

25

What kind of urolith is most common in cattle?

Silica or struvite

26

What are the two most common uroliths in canines?

Struvites + Calcium oxalate

27

What is the most common type of urolith in otters?

Calcium oxalate

28

What bacteria is specific to bovine urinary tracts?

Corynebacterium renale
-- and --
Arcanobacterium pyogenes

29

What bacteria is specific to the swine urinary tract?

Eubacterium suis

30

What do the bacteria listed in this lecture tend to cause in the kidney?

Plelonephritis

31

Term: Pyleonephritis

Thick, red, rough, granular or exudative mucosa
Dilation of renal pelvis
Ulceration of papilla

32

Why is the focus of inflammation in the renal pelvis?

Ascending

33

What causes leptospirosis?

Leptospira interrogans

34

What species are most affected by lepto?

Cattle + Dogs

35

What is seen histologically with lepto infecton?

Mononuclear inflammation in interstitium
Chronic interstitial nephritis

36

What age is most affected by the canine herpes virus?

4 to 6 week old puppies

37

Where do these puppies tend to get canine herpes virus?

intruterine or neonatal infection

38

What is seen throughout the kidney with canine herpes infections?

Hemorrhaging

39

What is seen histologically with canine herpes virus?

Acute tubular necrosis
Intranuclear eosinophilic viral inclusions

40

What type of hypersensitivity is seen with FIP?

Type 4 - cell mediated

41

What lesions are seen with FIP?

Pyogranulomatous nephritis secondary to fibrinoid vasculitis
Subcapsular + cortical foci of inflammation centered around blood vessels w/ pools of fibrin

42

What gross lesions are seen with FIP?

Vascular associated + granular texture

43

What is a differential that looks similar to FIP?

Lymphoma

44

What is a primary tumor of the kidney?

Renal cell carcinoma

45

What does renal cell carcinoma look like grossly?

Rounded, firm
Often hemorrhaging present
Cystic degeneration

46

What is a paraneoplastic condition of renal cell carcinoma?

Erthropoietin oversecretion resulting in polycythemia

47

What can be associated with renal cell carcinoma in german shepherds? What is seen grossly?

Nodular dermatofibrosis
Lesions will be seen in skin

48

What animal commonly gets renal cell carcinoma?

Budgerigars

49

What is the most common type of neoplasia in dogs?

Transitional cell carcinoma

50

What does TCC look like grossly?

Cream colored, raised and contains polypoid mass
Thickened mucosa

51

Where is TCC most commonly found in the bladder?

Around the trigone

52

What is the most common type of mesenchymal tumor in the urinary tract?

Leiomyoma

53

What is the cell origin of a leiomyoma?

Smooth muscle

54

What is the histological pattern of a leiomyoma?

Steaming bundles of smooth muscle cells

55

What is the gross appearance of a leiomyoma?

Smooth, nodular or bulging
Pale tan
Firm with streaming pattern

56

Where do leiomyomas form?

Ureter + Urethra + urinary bladder

57

What is the most common renal tumor in dogs?

Renal cell carcinoma

58

Which occurs more in dogs and cats primary renal tumors or secondary renal tumors? By how much?

Secondary
Cats - 7x's
Dogs - 2x's

59

What are the most common renal metastases in dogs?

Hemangiosarcoma
Adenocarcinoma
Lymphoma

60

What are the most common renal metastases in cats?

Lymphoma

61

What is a common renal tumor in pigs and chickens?

Nephroblastoma

62

What is the origin of nephroblastoma?

Pluripotent
Have mesenchymal + Tubular + Glomerular

63

What is the most common tumor in cattle?

Bovine leukemia virus - associated renal lymphoma