SI3 Flashcards
Anemia is
Not a disease, it’s a symptom
Decreased Hgb
Often r/t to iron def or chornic blood loss
C: Very young, very old, poor diet, women in repro years
SS: Pallor, glossitis, cheilitis
Tx Tx underlying cause, iron supplements, blood trsnfusion, nutriton
Glossitis
Swollen tonguw
Cheilitis
Swollen lips
Defective DNA synth of RBCs
Patho: Often r/t folic acid and Vit B12 Def
Tx Supplemental Vit
Dimished availability of erythrocyte precursors
Often lead to aplastic anemia
C: Renal dx, autimmune malignancy
SS: high ferritin and iron stores
Rarely w/ blood transfusion, often with EPO supplement
Acute blood loss causing anemia
May lead to hypobolemic shock, internal hemorrhage or tetroperitoneal bleed
C: Caused by trauma
SS: Pain that cant be explained otherwise
- Very bad back pain in LQ
Tx: Stop bleeding, tx pt, monitor lavs
Hemolytic anemia
Destruction of RBCs at a rate that exceeds production
Extrinisc (More common)
Damaged spleen
Intrisnic: SIckle cell
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Sickle Cell Crisis SS
Pain+++, swelling, pallor of mucous membranes, fever, jaundice , vasooccluisve crisis - tachypnea, HTN, NV
Complications of sickle cell crisis
Gradual involvment of all body systems - spleen, lungs kidney and brain
Prone to infection, acute chest syndrome
Diagnostics of sickle cell anemia
Peripheral blood smear, sickl8ing test, electrophroesis of hgb, MRI
Genetic
Nursing mgmt of sikcle cell anemia
Aoid hifh altritiurdes, maintain fluid intake , tret infections, help with pain control, supplemental O2
Acute ches tsyndrome: Abx, O2, Fluid, transfusion
CURE: Stem cell transplant
Immune Thrombocytopenic purpura
Abn destruction of circulating platletsSS: Gums and nose bleed, purpura (Non blanching)
Tx: Corticosteriods splenectemy
HIT
Immune system cause splts to clot in presence of heparin
SS: Heparin causes pts plts count to fall 50% + From baseline
Tx: d/c heparin
Disseminatied intravascular coagulation
Abnormally initiated and accelerated clotting
SS: Bleeding out of everywhere
Tx: Underlying cause - must diagnose quickly, often too late
Leukemia BE ABLE TO INTERPRET what labs would look like for leukemia
Common in adults
Abrupt - dramatic onset, serious infection or abn bleeding
Sky high WBC - 80s to 100s (Blasts- immature)
Hyperplasia of bone marrow and spleen
Often responds well to chemo
Low RBC and Plt count bc there’s not room in the bone marrow for that
ALL Leukemia
Common in kids
SS: Fever, bleeding, fatigue, CNS manifsestations
More difficult to tx
CML Leukemia
Genetic marker - philadelphia chromosome
Can be well controlled w/ tx
Chronic onset - swelling of spleen, liver, lymph nodes - bleeding bruising
CLL
Lymphoma vs leukemia
Leukemia: Originates in bone marrow/blood
SS: Blood marrow crowed by increased WBC
DIfference in location causes difference in ss
Risk factors of sickling
Significant blood loss
Illness
Climbing/flying at high altitudes
Keeping continued stress (mental/physicaal)
Low fluid intake
Elevated temp (fever)
Manifestation of cirrhosis
Jaundice
Skine lesions - Spiders and red palms (low levels of estrogen)
Hematologoical problems
Periph neuropathy - vitamin def and malnoutrish
Esophaogeal varices causing anemia
Know the two types of encephalopathy
Portal vein hypertension
Increase in BP in protl venous sytem r’t liver blockage
SS May lead to large swollen veins that can rupture and bleed
Tx: Propranolol