Flashcards in SIADH Deck (6)
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1
Define
1. Inappropriate secretion from posterior pituitary
2. Ectopic production
2
Pathophysiology
+ADH->excessive reabsorption of water in distal neprhon, not inhibited by hyponatremia.
Plasma osmolality falls
3
Calculate plasma osmolality
2 X sodium + urea + glucose
4
Diagnosis made
Comparison of plasma oxmolality and urine->urine osmolarity inappropriately elevated
5
Drug mechanism
1. +ADH
2. Potentiate effects
3. Unknown mechanism
6
