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Internal Medicine > SIADH > Flashcards

Flashcards in SIADH Deck (6)
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1

Define

1. Inappropriate secretion from posterior pituitary
2. Ectopic production

2

Pathophysiology

+ADH->excessive reabsorption of water in distal neprhon, not inhibited by hyponatremia.
Plasma osmolality falls

3

Calculate plasma osmolality

2 X sodium + urea + glucose

4

Diagnosis made

Comparison of plasma oxmolality and urine->urine osmolarity inappropriately elevated

5

Drug mechanism

1. +ADH
2. Potentiate effects
3. Unknown mechanism

6

Causes

1. Drugs
AntiD, antipsychotics
Chemotherapy
Omeprazole
2. Post-operative stress
3. CNS
Infections
Stroke
Trauma
Neurosurgery
4. Pulmonary
Pneumonia
TB, empyema
Status asthmaticus
5. Malignant
Neoplasm
Lymphoma
Leukemia
Mesothelium
Ewings sarcoma
6. Psychoses
7. Vasopressin or oxytocin

Decks in Internal Medicine Class (67):

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