Sickle Cell Anemia (Online Lecture) Flashcards
how do you get sickle cell
inherited
what do sickle cell RBC look like
hard and pointed, not round
how long do sickle cells live for
10-20 days
if sickle cells only live for 10-20 days what other issue is present
anemia
sickle cell trait
individual has inherited the gene for sickle cell, will not develop into the disease
however sickle cell mom and dad will equal sickle cell child
average life expectancy
40 years
sickle cell cure
no clue, close is a bone marrow transplant
what type of anemia is sickle cell
hemolytic
what are some things that can exacerbate sickle cell crisis
low O2 levels
dehydrated
cold temp
example of low O2
mountain climbing
why does dehydration affect sickling
increased blood viscosity
why does cold temp impact sickling
vasoconstriction and slows blood flow
when sickle cells are crystalized they stick to endothelial and decrease blood flow which results in
ischemia/injury/infarction
what can revert cells back to normal shape
oxygen
when the blood vessel is inflamed this predicates
more sickling
