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Exam 11 > Sigdel 2 > Flashcards

Sigdel 2 Flashcards

1
Q

Cells with nucleus protruding

A

Collecting duct (Bellini duct) carcinoma

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2
Q

Has tubule papillary architecture with desmoplastic stroma (a lot of fibrosis)

A

Collecting duct (Bellini duct) carcinoma

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3
Q

Poor prognosis > responds poorly to chemo

A

Collecting duct (Bellini duct) carcinoma

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4
Q

Young pts. Translocation of TFE3 gene at Xp11.2

A

Xp11 translocation carcinoma

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5
Q

Overproduction of TFE3 transcription factor. Papillary architecture

A

Xp11 translocation carcinoma

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6
Q

Arise from urothelium of renal pelvis. Causes hematuria, hydronephrosis, flank pain

A

Urothelial carcinoma of renal pelvis

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7
Q

Has triphasic histo of blastemal cells, stromal cells, epithelial type cells

A

Wilms tumor

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8
Q

Aniridia, genital anomalies, mental retardation

A

WAGR

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9
Q

Gonadal dysgenesis (male pseduohermaphraditism), early onset nephropathy

A

Denys-drash

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10
Q

Organomegaly. WT2 gene

A

Beckwith-Wiedemann

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11
Q

Aggressive with hobnail cells

A

Collecting duct (Bellini duct) carcinoma

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Exam 11 (15 decks)

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