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Exam 11 > Sigdel > Flashcards

Sigdel Flashcards

1
Q

No 3p alteration

A

Renal papillary adenoma

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2
Q

Tubule papillary architecture

A

Renal papillary adenoma

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3
Q

Benign,

A

Renal fibroma (hamartoma)

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4
Q

Incidental finding. In pyramids

A

Renal fibroma (hamartoma)

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5
Q

Fibroblast like cells, collage nous tissues, entrapped tubules at periphery

A

Renal fibroma (hamartoma)

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6
Q

Multiple masses of angiomyolipomas indicate

A

Tuberous sclerosis

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7
Q

Has spindle and Epitheloid cells

A

Angiomyolipoma

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8
Q

AD with LOF of tumor suppressor genes (TSC1 on Chr _____ and TSC2 on Chr _____). Also lesions on cerebral cortex, skin abnormalities, other benign tumors

A

Tuberous sclerosis
9.
16.

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9
Q

Adults > 50. Men. Incidental finding. Usually multifocal. Benign, but may coexist with RCC

A

Oncocytoma

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10
Q

Mahagony brown tumor. Fibrosis in middle

A

Oncocytoma

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11
Q

Mostly sporadic. Major risk factor is tobacco. Arises from renal tubular epithelium

A

RCC

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12
Q

Costovertebral pain, palpable mass, hematuria

A

RCC

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13
Q

Only treatment is nephrectomy

A

RCC

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14
Q

Mets to lung and bones

A

RCC

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15
Q

Most common. Loss of sequences on short am Chr 3 (VHL - tumor suppressor genes). AD. Pancreas, liver, and kidney cysts. Hemangioblasts in retina and cerebellum

A

Clear cell type RCC

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16
Q

Papillary growth pattern. Multifocal. Associated with dialysis

A

Papillary RCC

17
Q

Has schamomma bodies > calcium deposition

A

Papillary RCC

18
Q

Sporadic form most common. Trisomies 7,16,17. Loss of Y in males

A

Papillary RCC

19
Q

Familial form. Trisomy 7 (has MET locus - protooncogene tyrosine kinase receptor)

A

Papillary RCC

20
Q

Prominent cell membrane with nuclear clearing

A

Chromophobe RCC

21
Q

Use stain of hale’s colloidal iron (cells stain blue)

A

Chromophobe RCC

22
Q

Benign. Incidental finding at autopsy or body imaging. Needs long term hemodialysis.

A

Renal papillary adenoma

Exam 11 (15 decks)

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