silly notebook notes Flashcards

1
Q

enzyme inducing anti-epileptic drugs, what can they not be used with

A

carbamazepine
phenytoin
topiramate

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2
Q

vascular dementia on SPECT

A

patchy reduced attenuation through out brain

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3
Q

wernickes sx that delirium tremens dont have

A

wide based ataxia
ophthalmoplegia

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4
Q

passivity phenomena

A

belief that thoughta/actions are controlled by external agent

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5
Q

ideas of reference

A

false belief that random or irrelevant occurences directly relates to them

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6
Q

antipsychotic for someone with diabetes + hypertension

A

aripiprazole

(?low side effect profile)

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7
Q

overvalued idea example

A

anorexic thinks they’re “horribly fat”

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8
Q

where does fluid go when supine

A

hepatorenal recess

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9
Q

where does it go in aspiration pneumonia

A

right lower lobe

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10
Q

chlamydia microbio

A

does NOT stain with gram
intracellular organism that produces both elementary bodies + reticulate bodies during cell cycle

diagnosed by PCR

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11
Q

when would u give clozapine

A

treatment resistant schizo

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12
Q

whats uhthoff phenomenon and when does it occur

A

transient worsening of neurological symptoms related to a demyelinating disorder on increased temp (exercise, fever, hot tubs)

MS

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13
Q

L’Hermittes sign

A

an electric shock-like sensation that occurs on flexion of the neck. This sensation radiates down the spine, often into the legs, arms, and sometimes to the trunk

can indicate MS

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14
Q

serum Na in SIADH

A

low Na due to excessive dilution

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15
Q

wheres brocas area and damage to it causes what

A

left frontal gyrus

expressive dysphasia

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16
Q

wheres wernickes

A

left posterior superior temporal gyrus

receptive dysphasia

17
Q

right hemiparesis + dysphagia stroke

A

middle cerebral artery

18
Q

reversal of heparin

A

protamine sulphate

19
Q

increase or decrease potassium increases digoxin toxicity

A

hypOkalaemia

careful with furesomide

20
Q

clopidogrel MoA

A

antagonist against adenosine diphosphate receptor

21
Q

neutropenic sepsis prophylaxis

A

fluroquinolone
(levofloxacin, ciprofloaxcin)

22
Q

embden-myerhof pathway

A

anarobic glycolysis pathway - generates ATP + NADH (reveres Fe3+ to Fe2+)

NADH acts as electron donor preventing oxidation of Fe2+ to Fe3+
(generates NAD+ in process)

23
Q

hexose monophosphate shunt

A

generates NADPH
protects against oxidative stress
*regenerates glutathione

RATE LIMITING ENZYMES = G6PD

24
Q

glutathione

A

protects from free radical with unpaired electrons (hydrogen peroxide) by reacting with it to form water + oxidase glutathione product (GSG)

-> maintains redox balance
-> replenised via hexose monophosphate shunt

25
Q

rapaport-lubering shunt

A

generates 2,3, DPB that right shifts oxygen dissociate curve + allows more O2 to be released