Skeletal Flashcards
(117 cards)
Components of skeletal system: (4)
Bones, cartilages, tendons, ligaments
Functions of Skeletal system:
- Body support and movement,
- organ protect,
- mineral storage,
- blood cell production
Connective tissues of the Skeletal
system:
- determined by the composition of their:
Bone, cartilage, tendons, and ligaments
EXTRACELLULAR MATRIX
ALWAYS contains collagen, ground substance, water, and molecules
Matrix
A fibrous protein, provides flexibility, resists pulling/compression
Collagen
Contains proteoglycans (water trapping proteins), helps cartilage to be smooth and resilient
Matrix ground substance
Contains LARGE AMOUNTS of collagen, fibers, it is very tough like ropes/cables
Extracellular matrix
Bone matrix by weight
- 35% organic
- 65% inorganic
The organic material of the bone matrix is primarily
Collagen and Proteoglycans
The inorganic material of the bone matrix is primarily
- Calcium phosphate crystal called
- “hydroaxyapatite” Ca10(PO4)6(OH)2
Lend flexible strength to the bone
Collagen fibers
Gives bone compression strength
Mineral component
Formation of the bone and repair/remodeling
Osteoblasts (born to build)
Osteoblasts produce
- Collagen
- Proteoglycans
Also secrete high concentrations of Ca2+ and phosphate ions, forming crystals (hydroxyapatite)
Osteoblasts
Formation of NEW BONE by osteoblasts is called
Ossification
Cells that maintain bone matrix, form from osteoblast after bone matrix has surrounded it
Osteocytes
% of osteocytes
90-95% of bone cells
Bone matrix in spaces in the osteocyte cell bodies are called
Lacunae
Narrow and long spaces in the bone cells (cell extensions)
Canaliculi
Bone-destroying cells
Osteoclasts
Contributes to the bone repair and remodeling, removing existing bone
Osteoclasts
Removing existing bone is called
Bone reabsorption
Bone breakdown is important for mobilizing
Ca2+
calcium carion