skin 12: summary Flashcards Preview

Micro > skin 12: summary > Flashcards

Flashcards in skin 12: summary Deck (39):
1

Need to know ALL names for agent/disease!

Variola virus – smallpox:
VZV - chickenpox and zoster
Human Parvovirus B19 (HPV B19) - Erythema infectiosum (aka Fifth disease)
(HHV-6) or (HHV-7) - Exanthem Subitum
(aka roseola infantum aka Sixth disease)
Measles virus – measles (aka rubeola, aka hard measles)
Rubella virus - rubella (aka soft measles, aka German measles)

2

Host and Reservoir: Humans are the source of infection:

Variola virus, Varicella-zoster,
HPV B19, HHV-6, HHV-7, measles virus, rubella virus

3

seasonality??

chickenpox, erythema infectiosum, measles, rubella

4

transmitted in respiratory secretions (primary mode):

variola, varicella-zoster, HPV B19, measles
and rubella virus

5

transmitted in lesions (secondary mode):

variola, varicella-zoster viruses

6

transmitted in saliva:

HHV-6, HHV-7

7

Primary POE is the URT inhalation of respiratory droplets:

variola, varicella-zoster, HPV B19, measles,
rubella viruses or direct inoculation of conjunctiva.

8

Primary POE is the oropharynx:

HHV-6, HHV-7.

9

Primary attack rate is high – thus asymptomatic infections are uncommon/rare:

varicella- zoster, measles virus; variola virus

10

Virus in lesion and lesions are infectious:

smallpox, chicken pox

11

Lesion is immune-mediated (virus not present):

erythema infectiosum, exanthem
subitum

12

Active, life-long infection:

HHV-6, HHV-7

13

Latent infections with recrudescence of virus infections:

varicella-zoster, HHV-6,
HHV-7

14

Persistent infections:

HHV-6, HHV-7, measles (SSPE), rubella (congenital infection)

15

Prodrome:

smallpox, chickenpox (primary infection in adolescents and adults),
erythema infectiosum (mild), measles, rubella (mild or absent)

16

Acute Disease: Fever and a maculopapular rash:

variola virus, varicella-zoster, HPV B19, HHV-6, HHV-7, measles virus, rubella virus

17

Acute Disease: Rash appears 1st on face, hand and forearms spreads to trunk, legs:

smallpox; rash/lesions are present on the palms of hands and soles of feet

18

Acute Disease: Rash appears 1st on face spreads to trunk, limbs:

chicken pox, measles, rubella

19

Acute Disease: Rash appears 1st on face, spreads to limbs (palms and soles), sometimes torso or
trunk:

erythema infectiosum

20

Acute Disease: Rash appears 1st on face and trunk, spreads to limbs:

exanthem subitum

21

Acute Disease: Fever defervesces then rash appears:

HHV-6 and HHV-7 (sometimes), variola virus,
HPV B19

22

Acute Disease: Fever with rash:

chickenpox, measles, rubella

23

Acute Disease: Arthropathy, arthralgia with fever, in adults, (more common in women) + rash:

HPV B19, rubella virus

24

complications: of all?

Secondary bacterial infection and/or bacterial superinfection of skin or RT

25

complication: Viral pneumonia, viral encephalitis

smallpox, varicella-zoster, measles

26

complication: Aplastic crisis

Fifth disease

27

complication: In utero infection

varicella-zoster, Fifth disease, HHV-6 (likely), measles, rubella

28

complication: Congenital disease

varicella-zoster, HPV B19, measles, rubella

29

complication: Reye's syndrome

varicella-zoster - aspirin contraindicated

30

complication: Diarrhea and pneumonia in malnourished populations

measles

31

complication: Otitis media in developed countries

measles

32

how to dx all viral exanthems

Clinical features, susceptibility, contact with infected person

33

how to dx congenital infections

TORCH/STORCH/TORCHS test

34

ddx: a person with a fever and maculopapular rash (excluding epidemiological factors such as age and seasonality):

all of above? + ECHOviruses, Coxsackie viruses enteroviruses 6871, arboviruses, Hepatitis B viruses, Dengue, Rocky Mountain Spotted Fever, Lyme Disease, Neisseria meningitidis, S. pneumoniae, scarlet fever, toxic shock syndrome

35

ddx: a person with arthropathy:

HPV B19, rubella virus, Lyme Disease, rheumatoid arthritis

36

Vaccine preventable -

smallpox, chickenpox, measles, rubella

37

Post-exposure prophylaxis with vaccine to prevent disease -

chickenpox vaccine.

38

Antiviral therapy -

chicken pox and zoster

39

Immune globulin -

chicken pox

Decks in Micro Class (61):