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Histology Exam Review > Skin > Flashcards

Flashcards in Skin Deck (28):
1

hairy skin is missing what layer?

stratum lucidum

2

the cells of the stratum basale are linked to the basal lamina via _________

hemidesmosomes

3

what is the thickest epithelial layer?

stratum spinosum

4

what are tonofibrils?

give mechanical strength to epithelium located in the stratum spinosum

5

what are lamellar granules?

membrane bound tubes that undergo exocytosis producing lipid rich barrier around cells to protect against water loss

6

what layer of epidermis do organelles disappear?

stratum lucidium

7

what are melanocytes formed from?

tyrosinase

8

what occurs in the stratum corneum?

aggregated keratin filaments are cross linked forming squames and serving as a scaffold for lipids and proteins that for a barrier.

9

brown or black pigmentation

eumelanin

10

pink or red pigmentation

pheomelanin

11

where are melanocytes located?

on the basal lamina of the stratum basale - not in the dermis!

12

depigmentation caused by loss / increased activity of melanocytes

vitilago

13

how do moles form? proper name?

melanocytes divide normally for form theses - metaplasia
-benign menanocyte nevi

14

where are merkel cells located?

stratum basale

15

where are langerhans cells located?

stratum spinosum

16

what type of collagen is found in the papillary dermis?

type 3 collagen
-lots of cells and elastic fibers

17

what type of collagen is found in the reticular dermis?

type 1 collagen
-thick elastic fiber and few cells

18

what provides tactile sense in the dermal papillae?

meissner's corpuscle

19

what provides a sense of vibration and pressure in the hyprodermis?

Pacinian corpuscles

20

how does aging affect the skin?

-increased cross linking of collagen
-loss of elastic fibers
-dermis and epidermis are more loosely bound
-keratinocyte turnover decreases

21

what three things are located in the hypodermis?

blood vessels, adipose tissue, pacinian corpuscles

22

where do eccrine gland open to?

epithelial surface

23

how do both eccrine and apocrine sweat glands release their contents?

via merocrine glands = exocytosis

24

where are apocrine glands located?

auxilla, areolar region, anal regions

25

what is the difference in the lumens of eccrine vs apocrine glands?

eccrine glands - reabsorb salts and occluded
apocrine glands- big open lumen

26

how do sebaceous glands release their contents?

halocrine secretion - cell dies and it ruptures

27

type of collagen found in the papillary dermis vs. the reticular dermis?

papillary dermis- type 3 collagen
reticular dermis - type 1 collagen

28

mesissner's corpuscle location and function vs. pacinian corpuscle?

mesissner's corpuscle - in dermal papillae- tactile sense
pacinian corpuscle - hypodermis - vibration and pressure