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Pharmacology HOSA > Skin Disorder Topical Drugs > Flashcards

Skin Disorder Topical Drugs Flashcards

(79 cards)

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1
Q

Antipsoriatic

A

Drug used to treat psoriasis

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2
Q

Antiseptic

A

Agent that stops, slows, or prevents the growth of microorganisms

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3
Q

Germicide

A

Agent that kills bacteria

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4
Q

Keratolytic

A

Agent that removes excessive growth of the epidermis

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5
Q

Necrotic

A

Pertaining to death of tissue

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6
Q

Onychomycosis

A

Finger or toenail infections

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7
Q

Proteolysis

A

Enzymatic action that helps remove dead soft tissues by reducing proteins to simpler substances

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8
Q

Purulent exudate

A

Fluid discharge of pus and white cells

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9
Q

Superinfections

A

Overgrowth do bacterial or fungal microorganisms not affected by the antibiotic being administered

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10
Q

Tinea corporis

A

Superficial fungal infection, aka ringworm

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11
Q

Tinea cruris

A

Superficial fungal infection of the grown region, aka jock itch

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12
Q

Tinea pedis

A

Superficial fungal infection of the foot, aka athletes foot

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13
Q

Tinea versicolor

A

Fungal infection that concentrates on the trunk of the body occurring in adolescents and young adults

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14
Q

Topical antibiotics MOA

A

Direct local effect on specific microorganisms and may be bactericidal or bacteriostatic

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15
Q

Bacitracin MOA

A

Inhibits cell wall synthesis

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16
Q

Topical antibiotics use

A

Treat primary and secondary skin infection, prevent infection of minor cuts, wounds, scrapes, and minor burns, treat acne vulgaris

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17
Q

Topical antifungal drugs MOA

A

Local effect by inhibiting growth of fungi

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18
Q

Topical antifungal drugs uses

A

Athletes foot, jock itch, ringworm, cutaneous candidiasis, other superficial fungal infections of the skin

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19
Q

Topical antiviral drugs use

A

Inhibit viral activity during initial HSV episodes, and directly in lesions to speed up recovery

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20
Q

Docosanol use

A

Speeds healing

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21
Q

Acyclovir administrations

A

Has a topical form (for oral HSV)

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22
Q

Penciclovir administration

A

Has a topical form for oral HSV

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23
Q

Topical anti infective side effects nature

A

Mild

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24
Q

Topical anti invectives side effects

A

Rash, itching, urticaria, dermatitis, irritation, or redness (May indicate allergic reaction)

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25
Prolong use of topical antibiotics can result in...
A superficial superinfection
26
Topical antibiotics precautions
Pregnancy (cat C) and lactation
27
Acyclovir precautions
Pregnancy (cat B) and lactation
28
Penciclovir precautions
Pregnancy (cat B) and lactation
29
Econazole precautions
Pregnancy (cat C) andlactaton
30
Ciclopirox precautions
Pregnancy (cat B) and lactation
31
Topical feminized and antiseptics MOA
Affect a variety of microorganisms
32
Topical antiseptics and germicides use
Reduce the number of bacteria on skin surfaces, as a surgical scrub and preoperative cleanser, for preforming hand hygiene before and after caring for patients, in the home to cleanse the skin, and on minor cuts and abrasions to prevent infection
33
Topical antiseptics and germicides side effects
Few, but occasionally, there can be an allergic reaction which can cause skin rash or itching (should discontinue if allergic reaction occurs)
34
Topical corticosteroids MOA
Exert localized anti inflammatory activity, and reduce itching, redness and swelling
35
Topical corticosteroids use
Psoriasis, dermatitis, rashes, eczema, insect bites, and 1st and 2nd degree burns, including sunburns
36
Topical corticosteroids Side effects
Localized burning, itching, irritation, redness, dryness, allergic contact dermatitis, and secondary infections and systemic hypothalamic-pituitary-adrenal axis suppression, Cushing syndrome, hyperglycemia and glycosuria
37
Topical corticosteroids side effects are more likely to occur when...
Occlusive dressings are used
38
Topical corticosteroids contraindications
as Mono therapy for bacterial skin infections, for use on the face, groin, or axila, and for ophthalmic use, and not used as sole therapy in widespread plaque psoriasis
39
Topical corticosteroids precautions
Pregnancy (cat C) and lactation
40
Topical immunomodulators MOA
Reduce inflammation by stopping the production of cytokines and aren’t systemically absorbed (so can be used on the face and neck)
41
Topical immunomodulators use
Short term flare ups of atopic eczema, actinic keratosis (sun or aging spots), genital or perianal warts, some skin cancers
42
Topical immunomodulators side effects
Localized to skin tissues, and include burning, itching, and skin redness, may develop photosensitivity and flu like symptoms
43
Topical immunomodulators contraindications
Immunocompromised patients, long term use,
44
Topical immunomodulators precautions
Pregnancy and lactation
45
Tacrolimus contraindications
Allergy to macrolides
46
Fluorouracil use
Actinic keratosis topically, but it should be handled like a chemo agent
47
Topical antispsoriatics MOA
Helps to remove the plaques associated with the disorder
48
Antipsoriatics use
Psoriasis
49
Topical antispsoriatics side effects
Burning, itching or skin irritation
50
Anthralin side effects
Skin irritation or temporary discoloration of the hair and fingernails
51
Anthralin precautions
Pregnancy (cat .c) and lactation
52
Calcipotriene precautions
Pregnancy (cat C) and lactation
53
Topical enzymes use
Used to help remove necrotic tissue from chronic dermal ulcers, severely burned areas (2nd and 3rd degree burns)
54
Topical enzymes MOA
Hasten the reduction of proteins into simpler substances
55
Collagenase side effects
Mild transient pain and possibly numbness and dermatitis, but there is a low incidence of side effects
56
Topical enzymes contraindications
Wounds in contact with Major body cavities or where nerves are exposed or in fungating neoplasticism ulcers
57
Topical enzymes precautions
Pregnancy (cat B) and lactation
58
Topical enzymes interactions
Enzymatic activity can be impaired by certain detergents and heavy metal ions (Mercury and silver), which are used in some antiseptics
59
Optimal pH for collagenase
6 to 8, higher low lower pH decreases activity
60
Keratolytics uses
Warts, calluses, corns, seborrheic keratoses
61
Keratolytics side effects
Usually well tolerated, but a transient burning, rash, dry skin, scaling, or flu like syndrome can occur
62
Keratolytics contraindications
Moles, birthmarks, warts with hair, genital or facial warts, warts with mucous membranes, or on infected skin, prolonged use in infants, people with diabetes, or with impaired circulation
63
Keratolytics precautions
Pregnancy (cat C) and lactation
64
Topical anesthetics MOA
Temporarily inhibit the conduction of impulses from sensory nerve fibers
65
Topical anesthetics use
Releve itchin and pain caused by skin infections such as minor burns, fungal infections, insect bites, rashes, sunburn, and plant poisoning (poison ivy), some are applied to mucous membranes
66
Local anesthetics side effects
Local irritation, dermatitis, rash, burning, stinging, and tenderness
67
Topical anesthetics precautions
Class 1 antiarrhythmics because toxic effects are additive and possibly synergistic
68
Topical meds pediatric considerations
Since infants and children have a high ratio of skin surface area to mass, they are at a greater risk of systemic side effects with topical meds
69
Calcipotriene elderly considerations
Adults older than 65 are at risk for more skin related side effects
70
Topical antibiotics ex
Azelaic acid, bacitracin, benzoyl peroxide, clinamycin, gentamicin, metronidazole, mupirocin, retapamulin
71
Antifungal drugs ex
Butenafine, ciclopirox, clotrimazole, econazole, eficonazole, gentian violet, ketoconazole, luliconazole, miconazole, naftifine, nystatin, oxiconazole, sertaconazole, sulconazole, terbinafine, tolnaftate, tavaborole
72
Topical antivirals ex
Acyclovir, docosanol, penciclovir, vidarabine
73
Topical antiseptics and germicides ex
Chlorhexidine, hexachlorophene, oxychlorosene, povidone-iodine, sodium hypochlorite, triclosan
74
Topical corticosteroids ex
Alclometasone, amcinonide, betamethasone, desoximetasone, dexamethasone, diflorasone, fluocinolone, fluocinonide, flurandrenolide, hydrocortisone, triamcinolone
75
Topical immunomodulators ex
Imiquimod, ingenol mebutate, pimecrolimus, tacrolimus
76
Antispsoriatics ex
Anthralin, calcipotriene, selenium sulfide
77
Enzyme preparations ex
Collagenase, enzyme combinations
78
Keratolytics ex
Masoprocol, salicylic acid
79
Local anesthetics ex
Benzocaine, dibucaine, lidocaine, butamben picrate

Pharmacology HOSA (37 decks)

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