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Flashcards in Specific pathogen groups Deck (17):
1

Legionella name

Legionella pneumophilia

2

Legionella gram

Negative rod
Aerobic

3

Where does legionella live?

Soil, warm water, moist areas
Chlorine tolerant.

4

Legionella transmission

Usually inhalataion but you can get it from swimming in water.
No human to human.

5

Legionairre's disease

atypical lobal pneumonia
1-5% of CAP
incubation 2-10 days

6

Legionairre's fatality

30%

7

Legionairre's symptoms.

Fever, malaise, myalgia, anorexia, headache, cough, chest pain,system involvement.

8

Legionairre's systemic symptoms

GI- diarrhoea, pancreatitis, peritonitis
Neuro- headache, enceph
Heart- myocarditis, pericarditis, endo
Acute renal failure.

9

Pontiac fever

90% of legionella
Flu like symptoms
Recovers in 1 week
No treatment.

10

Diagnosis legionella

sputum culture 3-5 days
Urinary sample= hours
serology 4-8 weeks

11

Treatment legionella

Clarithromycin +- rifampicin
Doxy
Notify public health.

12

Pseudomonas source

water, soil, plant, animals, hot tubs, moist environments
hospital disinfectants, food, sink, showers, mops etc

13

Pseudomonas transmission

human to human
human to source
ingestion of food/water
opportunistic from nosocomial.

14

Pseudomonas structure

have pili to attach to host
capsulated
cytotoxins and proteases locally invade and disseminate.

15

Pseudomonas presentation

severe HAP immunocompromised
eye- keratitis, ear- otitis externa, skin, hot tub folliculitis, surgical wounds, bone- osteomyelitis, septic arthritis, CNS- meningitis, brain abscess, UTI, Pneumonia- COPD, CCF, CF, ventilated

16

Pseudomonas diagnosis

MacConkey agar and others.

17

Pseudomonas treatment

biofilm makes it hard
pencillin+cephalosporin?