Flashcards in Spinal Cord Lesions Deck (19):
A patient that has muscle atrophy, negative babinski, downgoing toes, fasciculations and flaccid paralysis in adults; hypotonia?
A patient that has muscle atrophy, negative babinski, downgoing toes, fasciculations and flaccid paralysis in infants? What kind of baby do you get? Inheritance
Spinal muscular atrophy
A patient with polio with show what in CSF? also where would you recover the virus?
High WBC and protein but normal CSF glucose
Scanning Speech, Intention Tremor and nystagmus?
Part of DCML and spinothalamic
Both muscle atrophy, negative babinski, downgoing toes, fasciculations and flaccid paralysis in adults; hypotonia AND Hypertonia hyperrflexia?
ALS is caused by?
Superoxide dismutase I
ALS Tx? Which one has shown to be the only one with survival?
MOA: glutamate antagonist
What does Superoxide Dismutase do?
Converts O2 to H2O2
Patient's pain temperature and motor skills are gone and only has fine touch sensory and proprioception left. Dx? Which spinal cord does it most likely affect and why?
Complete occlusion of anterior spinal artery
T4, Upper thoracic ASA is watershed area because the artery of adam only supplies up to T8
Patient loses ability of proprioception and progressive sensory ataxia. +Romberg Test and absence of DTRs. Dx and what is it associated with?
Tertiary Syphilis (Tertiary Syphilis)
1. Charcot joints
2. Argyll Robertson Pupils (accommodates but does not constrict to light)
Patient has bilateral loss of pain and teperature sensation at C8-T1. Dx? Why does this occur? What is it associated with?
Reason: Cystic cavity within the spinal cord
Associated with: Chiari
Demyelination of dorsal columns, lateral corticospinal tracts and spinocerebellar tracts and ataxic gait?
Subacute combined degeneration by Vitamin B12 deficiency
A patient who has frequent falling, nystagmus, High arched foot, hammer toes with kyphoscoliosis (Ataxia+multiple spinal cord tracts)? Dx? Cause of Death? Gene? and what does the gene do?
Dx: Friedreich Ataxia=GAA on chromosome 9 in frataxin gene
Cause of Death: Hypertrophic cardiomyopathy
Frataxin=>iron storage regulation
A patient with loss of all sensation at the level of lesion and Motor on the same side and loss of temperature and pain on the opposite side?
Bilateral loss of pain and decreased muscle strength?