Spinal Cord Lesions Flashcards Preview

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Flashcards in Spinal Cord Lesions Deck (19):
1

A patient that has muscle atrophy, negative babinski, downgoing toes, fasciculations and flaccid paralysis in adults; hypotonia?

Poliomyelitis

2

A patient that has muscle atrophy, negative babinski, downgoing toes, fasciculations and flaccid paralysis in infants? What kind of baby do you get? Inheritance

Spinal muscular atrophy

Floppy baby

AR

3

A patient with polio with show what in CSF? also where would you recover the virus?

High WBC and protein but normal CSF glucose

Fecal-Oral transmission

4

Scanning Speech, Intention Tremor and nystagmus?

MS

5

Polio affects?

Anterior Horn

6

MS affects?

Part of DCML and spinothalamic

7

Both muscle atrophy, negative babinski, downgoing toes, fasciculations and flaccid paralysis in adults; hypotonia AND Hypertonia hyperrflexia?

ALS

8

ALS is caused by?

Superoxide dismutase I

9

ALS Tx? Which one has shown to be the only one with survival?

Rilouzole

10

Rilouzole MOA?

MOA: glutamate antagonist

11

What does Superoxide Dismutase do?

Converts O2 to H2O2

12

Patient's pain temperature and motor skills are gone and only has fine touch sensory and proprioception left. Dx? Which spinal cord does it most likely affect and why?

Complete occlusion of anterior spinal artery

T4, Upper thoracic ASA is watershed area because the artery of adam only supplies up to T8

13

Patient loses ability of proprioception and progressive sensory ataxia. +Romberg Test and absence of DTRs. Dx and what is it associated with?

Tertiary Syphilis (Tertiary Syphilis)

Associated with:
1. Charcot joints
2. Argyll Robertson Pupils (accommodates but does not constrict to light)

14

Patient has bilateral loss of pain and teperature sensation at C8-T1. Dx? Why does this occur? What is it associated with?

Dx: Syringomyelia
Reason: Cystic cavity within the spinal cord
Associated with: Chiari

15

Demyelination of dorsal columns, lateral corticospinal tracts and spinocerebellar tracts and ataxic gait?

Subacute combined degeneration by Vitamin B12 deficiency

16

A patient who has frequent falling, nystagmus, High arched foot, hammer toes with kyphoscoliosis (Ataxia+multiple spinal cord tracts)? Dx? Cause of Death? Gene? and what does the gene do?

Dx: Friedreich Ataxia=GAA on chromosome 9 in frataxin gene

Cause of Death: Hypertrophic cardiomyopathy

Frataxin=>iron storage regulation

17

A patient with loss of all sensation at the level of lesion and Motor on the same side and loss of temperature and pain on the opposite side?

Brown-Sequard Syndrome

18

Bilateral loss of pain and decreased muscle strength?

Syringomyelia

19

What is wrong in Friedreich Ataxia?

Spinocerebellar tract