spleen Flashcards

1
Q

spleen is surrounded by?

A

a connective tissue capsule

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2
Q

the parenchyma of the spleen is divided in to two

A
  • red pulp

- white pulp

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3
Q

what does the white pulp & red pulp correspond to?

A

lymphocyte rich area (white)

blood rich area (red)

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4
Q

what forms the framework of the spleen

A

reticular connective tissue

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5
Q

what does the white pulp consist of?

A

-lymphocytic aggregations around the central arterioles

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6
Q

the central arteriole are branches of?

A

trabecular arteries which is a branch of the splenic artery

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7
Q

the white pulp is divided into 3 areas

A

-periarteriole lymphatic sheath (PALS)
-splenic nodule (malpighien nodules)
marginal zone

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8
Q

what is PALS and what does it consist of

A
  • aggregation of l.c that surrounds the central arteriole,
  • T-dependant area
  • show thinkenings knows as splenic nodules
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9
Q

what is the splenic nodule

A

B-dependent area,the central arteriol surrounded by the splenic nodule has an eccentric position

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10
Q

what is the marginal zone? and what does it consist of?

A
  • composed of loose lymphoid tissue
  • region between red and white pulps
  • contains marginal sinuses
  • rich in macrophages
  • B-depedant area
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11
Q

what does the red pulp consist of?

A
  • splenic cords (cords of billroth)

- splenic sinuses

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12
Q

the splenic cords

A
  • macrophages
  • plasma cells
  • cellular elements of blood
  • ** all situated in the loose mesh work of the reticular cells
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13
Q

the splenic sinuses

A

are wide cavities, which are lined by discontinous endothelium there are wide spaces between these cells

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14
Q

what is around the splenic sinuses

A

the basal lamina which is discontinous,

riticular fibers surround sinuses mainly in a transverse direction

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15
Q

what are the endothelial cells of the sinuses called?

A

stave cells

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16
Q

the central arterioles in the periphery of the white pulp or red pulp is called?

A

pulp arteries, which give several straight branches called the penicilliform arterioles

17
Q

where does the blood from the penicilliform arterioles flow to?

A

into the capillaries that may open into the intercellular space of the red pulp cells (open circulation)

18
Q

what is closed circulation

A

when the penicilliform arterioles open into the wide splenic sinuses