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Pharmacology > Statins > Flashcards

Statins Flashcards

1
Q

Examples

A

Atorvastatin, simvastatin

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2
Q

Mechanism

A
  • Competitive HMG-CoA Reductase inhibitor
  • Stop cholesterol synthesis -> ⬆️HDL, ⬇️LDL, ⬇️TG
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3
Q

Indications

A
  • Hypercholesterolaemia
  • Atherosclerosis
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4
Q

SE

A
  • Rhabdomyolysis, myositis
  • Abnormal LFT
  • GI disturbance
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5
Q

CI

A
  • Liver disease
  • Pregnancy
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Pharmacology (44 decks)

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