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Flashcards in STIs Deck (34):
1

incubation time for primary syphilis

3 weeks

2

incubation time for secondary syphilis

4-8 weeks after primary

3

incubation for tertiary syphilis

1-30 years

4

incubation for N. gonorrhoeae

2-6 for acute symptoms, days-weeks for disseminated

5

incubation for Clamydia

7-21 days

6

incubation for HPV

highly variable but usually 2-20 months

7

why would you culture in high CO2

older method to detect N. gonorrhoeae

8

how do you detect HPV

PCR

9

how do you detect N. gonorrhoeae and chlamydia?

urethral DNA probe

10

how do you Dx syphilis

RPR (rapid plasma reagin) or VDRL screen for Abs
false positives with other conditions so must be confirmed with FTA
primary syphilis can also be Dx with dark field microscopy, but not always avaialable

11

conditions which can cause false post RPR

SLE
mono
malaria
leprosy
hep A
HIV
pregnancy

12

gram stain

could ID N. gonorrhoeae as gram neg intracellular coffee-bean shaped diplococci

13

what is the lesion of primary syphilis

chancre- painless

14

chancroid

caused by H. ducreyi
painful
unilateral lymphadenopathy common
usually associated with sex trafficking or drug users

15

Tx for syphilis

IM Bicillin
one dose if yr

16

what organism causes syphilis

Treponema pallidum
spirochete

17

what is the lesion of HPV called

condyloma acuminata

18

how does HIV present

nonspecific viral syndrome with fever, sore throat, swollen lymph nodes, and transient maculopapular rash

19

Chlamydia trachomatis presentation

can first present with PID
lower abdominal pain
urinary frequency/dysuria
Fitz-hugh-curtis syndrome
cervicitis
can cause lymphogranuloma venereum

20

Tx Chlamydia

obligate intracellular therefore penicillins and cephaloporins not effective
use macrolides (azithromycin) or tetracyclines
and Tx for gonorrhea

21

Tx gonorrhea

ceftriaxone only option

22

Tx for trichomonas vaginalis

metronidazole
tinidazole

23

herpes simplex 2

painful cluster of vesicles which burst -> ulcers
incubation 4-7 days

24

Klebsiella granulomatous

causes granuloma inguinale
rare in US
can cause autoamputation

25

how do you Dx H. ducreyi

culture in chocolate agar

26

how do you Tx H. ducreyi

ceftriaxone
azithromycin
single dose of either

27

kelbsiella granulomatous Dx

Bx

28

kelbsiella granulomatous Tx

erythromycin or tetracyclin for 3 weeks
ampicillin for 12 weeks

29

Dx herpes simplex-2

viral culutres PCR
Tzanck smear

30

Tx of herpes simplex-2

acyclovir
famciclovir
valacyclovir

31

N. gonorrhoeae

PID
migratory polyarthritis
sparsely distributed necrotic pustules

32

genital ulcers

syphilis- painless
herpes- painful
chancroid- painful
lymphogranuloma venerum

33

urethritis and cervicitis

N. gonorrhoeae
Chlamydia

34

genital warts

HPV
secondary syphilis