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MED 2042 Wks 1-5 > STIs > Flashcards

Flashcards in STIs Deck (7)
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1

HIV

Retrovirus, infect CD4 T-helper cells

Opportunistic infection

Simultaneous antibody/antigen detection -(disagnosis)

HAART (treatment)

2

Order for HIV testin

Serum HIV ELISA
followed by Western Blot test

3

HPV

Viral proteins E6 and E7 disrupt cell division

Lesions, cervical intraepithelial neoplasia (CIN)

Prevention: quadrivalent vaccine (Gardasil)

4

HSV-2
(Herpes simplex virus) -associated with genital herpes

Transmitted by sexual contact

Neonatal herpes: infant exposed to HSV in birth canal

Commonly recurring

Confirm by lab tests( swab of lesion/vesicle fluid), PCR (more sensitive), HSV antigen detection

5

Chlamydia trachomatis

Serotypes D-K cause genital infections

Obligate intracellular bacterial pathogen

Watery/mucopurulent discharge, dysuria

Diagnosis: cell culture

Complications mainly in females- pelvic inflammatory disease, scarrin of fallopian tube leadin to ectopic pregnancy n infertility

Azithromycin (treatment)

6

Nisseria Gonorrhoea -
Causes gonorrhoea

Gram negative bac

Culture will show gram negative intracellular diplococci

Treatment: ceftriaxone IM with azithromycin

7

Treponema pallidum
-causes syphillis

Chancre (symptom)

Primary syphy: lesions
2ndary syphy: highly infectious skin rash
Tertiary syphy: granulomas from inflammation, cardiovascular, neurosyphyllis, psychotic symptoms

(Diagnosis)- non-treponemal tests -detect antibodies against cardiolipin
Treponemal tests

High dose penicillin (treatment)