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Microbiology Exam 2 > Straight up antibiotics > Flashcards

Straight up antibiotics Flashcards

1
Q

Mode of action: disrupt the phospholipoprotein membrane

A

mode of action polymyxins polyenes Azoles

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2
Q

Voriconazole

A

disrupt the phospholipoprotein membrane DOC for systemic mycosis, especially aspergillosis in AIDS patients Crosses BBB

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3
Q

Triazoles

A

disrupt the phospholipoprotein membrane Examples are Fluconazole (diflucan) and Voriconazole

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4
Q

Polymyxin E (colistin)

A

disrupt the phospholipoprotein membrane i. In Thayer-Martin Chocolate Agar ii. Treats otitis externa

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5
Q

Polymoxins

A

disrupt the phospholipoprotein membrane isolated from bacillus amphithatic Examples are polymyxin B and Polymyxin E (aka colistin)

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6
Q

Pencillins

A

Young G+ only (G+ have more murein) - G+ have higher internal pressure so breakdown of murein is drastic Examples are natural penicillins repository penicillins semi-synthetic penicillins Beta lactamase penicillins

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7
Q

aspergillosis

A

disrupt the phospholipoprotein membrane causes systemic mycosis dimorphic fungi in immunodifficent patients at 25*C looks like mold at 37*C looks like yeast

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8
Q

Fluconazole (diflucan)

A

disrupt the phospholipoprotein membrane DOC for deep or superficial Candidias

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9
Q

Mode of Action: suppress cell wall synthesis

A

mode of action penicillins cephalosporins carbapenems bactracin vancomycin

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10
Q

Natural penicillins

A

naturally occuring examples are benzyl penicillin (G) and phenoxymethyl penicllin (V)

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11
Q

Polyenes

A

disrupt the phospholipoprotein membrane toxic come from streptomyces treats fungal infections inhibits sterols Examples are Nustatin and Amphotericin B

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12
Q

Amphotericin B

A

disrupt the phospholipoprotein membrane i. Passes through BBB ii. IV if infection is serious iii. DOC for systemic mycosis caused by aspergillosis

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13
Q

Polymyxin B

A

disrupt the phospholipoprotein membrane i. Treats resistant actinobacter, otitis externa, ophthalmic infections ii. In triple antibiotic ointment iii. G- only iv. Toxic (Nephro/neurotoxin)

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14
Q

Azoles

A

disrupt the phospholipoprotein membrane Examples: Imidazoles Triazoles

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15
Q

Imidazoles

A

disrupt the phospholipoprotein membrane attack sterols Examples are clotrimazole, miconazole, and ketoconazole

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16
Q

Clotrimazole and Miconazole

A

disrupt the phospholipoprotein membrane Treats ringworm, athlete’s foot, volvovaginits (epidermopyton, microsporum, trichophyton)

17
Q

Nystatin

A

disrupt the phospholipoprotein membrane i. Treats dermatophytic (superficial) candidas albicans (thrush, vulvovagitis) Is a polyene

18
Q

mode of action polymyxins polyenes Azoles

A

Mode of action: disrupt the phospholipoprotein membrane

19
Q

disrupt the phospholipoprotein membrane DOC for systemic mycosis, especially aspergillosis in AIDS patients Crosses BBB

A

Voriconazole

20
Q

disrupt the phospholipoprotein membrane Examples are Fluconazole (diflucan) and Voriconazole

A

Triazoles

21
Q

disrupt the phospholipoprotein membrane i. In Thayer-Martin Chocolate Agar ii. Treats otitis externa

A

Polymyxin E (colistin)

22
Q

disrupt the phospholipoprotein membrane isolated from bacillus amphithatic Examples are polymyxin B and Polymyxin E (aka colistin)

A

Polymoxins

23
Q

Young G+ only (G+ have more murein) - G+ have higher internal pressure so breakdown of murein is drastic Examples are natural penicillins repository penicillins semi-synthetic penicillins Beta lactamase penicillins

A

Pencillins

24
Q

disrupt the phospholipoprotein membrane causes systemic mycosis dimorphic fungi in immunodifficent patients at 25*C looks like mold at 37*C looks like yeast

A

aspergillosis

25
Q

disrupt the phospholipoprotein membrane DOC for deep or superficial Candidias

A

Fluconazole (diflucan)

26
Q

mode of action penicillins cephalosporins carbapenems bactracin vancomycin

A

Mode of Action: suppress cell wall synthesis

27
Q

naturally occuring examples are benzyl penicillin (G) and phenoxymethyl penicllin (V)

A

Natural penicillins

28
Q

disrupt the phospholipoprotein membrane toxic come from streptomyces treats fungal infections inhibits sterols Examples are Nustatin and Amphotericin B

A

Polyenes

29
Q

disrupt the phospholipoprotein membrane i. Passes through BBB ii. IV if infection is serious iii. DOC for systemic mycosis caused by aspergillosis

A

Amphotericin B

30
Q

disrupt the phospholipoprotein membrane i. Treats resistant actinobacter, otitis externa, ophthalmic infections ii. In triple antibiotic ointment iii. G- only iv. Toxic (Nephro/neurotoxin)

A

Polymyxin B

31
Q

disrupt the phospholipoprotein membrane Examples: Imidazoles Triazoles

A

Azoles

32
Q

disrupt the phospholipoprotein membrane attack sterols Examples are clotrimazole, miconazole, and ketoconazole

A

Imidazoles

33
Q

disrupt the phospholipoprotein membrane Treats ringworm, athlete’s foot, volvovaginits (epidermopyton, microsporum, trichophyton)

A

Clotrimazole and Miconazole

34
Q

disrupt the phospholipoprotein membrane i. Treats dermatophytic (superficial) candidas albicans (thrush, vulvovagitis) Is a polyene

A

Nystatin

Microbiology Exam 2 (11 decks)

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