stress and disease Flashcards

1
Q

what is stress

A

Perceived or anticipated threat that disrupts a person’s wellbeing or homeostasis

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2
Q

stress is caused by—

A

stressors

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3
Q

homeostasis is

A

a state of balance among all the body systems needed for the body to survive and function correctly

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4
Q

allostasis

A

is the state of achieving new homeostasis due to a stressor

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5
Q

allostatic overload

A

Is when the stressor is significant and the body fails to reach a new equilibrium

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6
Q

What are the stress systems

A
  1. Hypothalamic-pituitary adrenal
  2. sympathetic nervous system
  3. Immune system
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7
Q

hypothalamic-pituitary adrenal

A

hypothalamus secretes– corticotropin hormone
pituitary secretes– adrenocorticotropin hormone
adrenal gland– cortisol

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8
Q

What does the acute release of cortisol do to the body

A
  • regulates sleep, mood, growth and reproduction, cognition, arousal, and cardiovascular tone
  • increases blood sugar level or stimulates glucogenesis
  • increases powerful anti-inflammatory and immunosuppressive agent
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9
Q

Chronic release of cortisol release leads to

A
  • sleep deprivation, obesity, type 2 diabetics, hypertension, less bone density
  • cognitive impairment and emotional disorder
  • gastric ulcers
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10
Q

Sympathetic nervous system activates the releasing of —–

A

Catecholamines which are norepinephrine and epinephrine

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11
Q

What are the effects of catecholamines

A
  • stimulates alpha and beta androgenic receptors
  • regulates the skeletal, cardiovascular, hepatic, immune system and pulmonary systems
    -increases proinflammatory cytokine production
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12
Q

chronic release of norepinephrine causes

A
  • stroke
    -plaque formation in the blood vessels
    -sickness syndrome
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13
Q

the immune system activates

A
  • responds to stress
  • alert other signals about the stress
  • stress can either suppress or enhance immune cell function by stimulating endogenous opiate
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14
Q

Chronic stress may cause

A
  • immune degranulation
  • decrease natural killers and T-cytotoxic
  • increase tumor growth and metastasis of tumor
  • burnout
  • chronic inflammatory responses include
    - cardiovascular disease, type 2 diabetics, osteoporosis, COPD, and arthritis
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15
Q

What are the effects of telomeres

A

increases cell death and causes early death

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16
Q

telomers—

A

Are genetic caps at the end of chromosomes that stop proliferation and protect genetic information

17
Q

coping is —-

A

is the process of managing stressful challenges

18
Q

Coping can be

A
  1. adaptive: cognitive and behavioral efforts to manage stressful conditions like exercise and mindfulness
  2. maladaptive: increases health deterioration
19
Q

general adaptive syndrome

A
  1. alarm stage
  2. resistance ( adaption stage)
  3. exhaustion stage ( allostatic overload)