Stroke Flashcards

1
Q

Stroke is the ____ leading cause of death in Canada.

A

stroke

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2
Q

Each year, more women than men die from stroke (T/F).

A

TRUE

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3
Q

Stroke is the leading cause of adult ___-____ disability in the world.

A

long-term

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4
Q

What are 6 modifiable risk factors for stroke?

A
  1. hypertension
  2. cardiac disease
  3. diabetes
  4. cholesterol
  5. smoking
  6. obesity
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5
Q

BP over what levels increases risk of stroke?

A

> 160/95

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6
Q

TIA is a warning sign but may also cause lasting damage (T/F)

A

TRUE

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7
Q

In a TIA, neurological deficits will resolve within ___ hours but may only last a few minutes.

A

24

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8
Q

___% of people who have a TIA have a recurrence in 1 year.

A

80

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9
Q

___% of people who have a TIA have a clinically significant stroke within 30 days after TIA.

A

20

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10
Q

Neurophysiological changes after TIA last at least ___ weeks.

A

2

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11
Q

Ischemic strokes = ___% of strokes

A

80

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12
Q

______ = occluding plaque, slower, symptoms evolve.

A

thrombosis

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13
Q

______ infarct = 20%, and there is a high rate of cognitive changes associated with these types of strokes

A

lacunar

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14
Q

_______ stroke = subgroup of ischemic stroke

A

lacunar

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15
Q

Lacunar stroke = smaller than ___ cm

A

1

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16
Q

Lacunar strokes are associated with what 2 co-morbidities?

A
  1. hypertension

2. diabetes

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17
Q

Lacunar strokes involve the small perforating _______.

A

arteries

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18
Q

Subcortical location and small infarction = pure ____ and _____ deficits.

A

motor; sensory

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19
Q

Embolic strokes = ___-__%, and can be air or water

A

20-30

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20
Q

Do embolic strokes have any warning?

A

no

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21
Q

What are the two types of strokes?

A
  1. ischemic

2. hemorrhagic

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22
Q

Hemorrhagic strokes = ___% of strokes

A

20

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23
Q

Hemorrhagic strokes = _____ and _____-____ malformation.

A

aneurysm; arteriole-venous

24
Q

Stroke has an _____ onset, but then slowly progress over minutes to hours.

25
If you get to the hospital between 1-3 hours after stoke you can be treated with what?
tissue plasminogen activator
26
______ score used to predict progression of stroke and risk of recurrent stroke.
ABCD
27
What is the ABCD score?
A: age B: blood pressure C: clinical features D: duration
28
A higher score on the ABCD score would indicate a worse risk (T/F).
True
29
What are 2 arterial factors that contribute to stroke?
1. vessel walls | 2. damaged vessels
30
What is a site in the brain that may have congenital malformation?
circle of willis
31
What are 4 venous factors that contribute to stroke?
1. Tendency for a persons blood to clot quickly 2. Irritation or inflammation of the inner lining of the vein 3. Slow or sluggish flow of blood through deep veins 4. Deep vein thrombosis
32
Anastomoses between ____ and ____ often help preserve leg motor and sensory function after stroke.
ACA; MCA
33
What 2 arteries are at risk in the neck?
1. vertebral arteries | 2. internal carotid
34
The vertebral and internal carotid artery can suffer spontaneous or traumatic injury (T/F).
TRUE
35
______ _____ = area of marginal perfusion
ischemic penumbra
36
______ and ______ neurons are sensitive to ischemia.
cerebellar; hippocampus
37
In response to an ischemic stroke, there is excess extracellular _____ ______.
glutamate apoptosis
38
_____-_____ degeneration occurs in response to ischemic stroke.
trans-neuronal
39
When ____ receptors are blocked, glutamate uptake is reduced and outcome improves.
NMDA
40
Higher dose, very early mobilization provolone was associated with a _____ in the odds of a favourable outcome at 3 months.
reduction
41
When giving TIA, the stroke cannot be ______.
hemorrhagic
42
TIA can salvage _______ tissue if given within 3 hours of onset.
pneunbral
43
What are 4 ways to prevent a recurrent stroke?
1. anticoagulation therapies 2. lipid lowering agents 3. lifestyle changes 4. exercise
44
What are the outcomes for stroke?
1. 25% minor impairment 2. 50% moderate to severe 3. 20-30% recover poorly and die by one year
45
__________ stroke better for long term prognosis for functional recovery.
hemorrhagic
46
Integrity of ________ motor output system is critical particularly for fractioned movement of the fingers
pyramidal
47
Even a small injury in the ______ ______ is very significant.
corona radiata.
48
____ ______ structure after stroke predicts change associated with motor learning.
white matter
49
Focal lesion to Broca's area = _____ aphasia.
expressive
50
Focal lesion to Wernickes area = ________ aphasia.
receptive
51
Apraxia = motor disorder caused by lesion to _______ _____ lobe.
posterior parietal
52
________ apraxia = can explain an action, perform it voluntarily but not complete movements on command.
ideomotor
53
_______ apraxia = cannot draw shapes
constructional
54
_________ apraxia = cannot create a motor plan to carry out complex actions; loss of ability to relate objects to their use,
ideational
55
The ________ capacity of the brain is highly reliant on high doses of skilled movement.
adaptive
56
Drugs that induce neuroplasticity are commonly used in stroke (T/F).
FALSE; drugs that induce neuroplasticity do not exist