Syphilis

Question 1

What is it ?

Answer 1

STI with treponema pallidum

Question 2

What is acquired syphilis ?

Answer 2

T pallidum enters via body fluids
- cuts
- sexual contact
- contaminated needles
- direct contact

Question 3

What is congenital syphilis ?

Answer 3

T pallidum infects baby in uterus or when exiting through vagina

Question 4

Features of primary syphilis ?

Answer 4

• 1-3 weeks after t pallidium lands on skin or mucous membrane
• painless ulcer
  ( raised border , hard base , fluid rich in spirochetes )
  ( resolves spontaneously within 3-6 weeks )

Question 5

Diagnostics

Answer 5

Serological test
Rapid plasma regain test
VDRL
Tepenemal test
TPPA
FTA-ABS

Question 6

Treatment

Answer 6

Penicillin G IM , single dose