T/B cell function Flashcards Preview

Immunology/Microbiology > T/B cell function > Flashcards

Flashcards in T/B cell function Deck (15)
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1
Q

What binds to the lower most part of an antibody?

A

Macrophage=>Fc Receptor

2
Q

Complement binds to the?

A

complement binding site on the Fc region (above Macrophage binding)

3
Q

Fc is?

A

Constant
ƒ Carboxy terminal
ƒ Complement binding
ƒ Carbohydrate side chains

4
Q

Fab is?

A

Fragment, antigen binding

5
Q

IgA is most commonly found in?

A

GI tract or Gut infections

6
Q

What does IgE do when it sees an allergen?

A

Cross-links

7
Q

What are the acute phase reactants?

A
C-reactive protein
Ferritin
Fibrinogen
Hepcidin
Serum amyloid A
8
Q

acute phase reactants are up or down regulated in inflammation?

A

Upregulated

9
Q

What does C3b do?

A

Opsonization (Binds to Bacteria)

10
Q

What does C3, 4, 5 a do?

A

anaphylaxis

11
Q

C5a?

A

Neutrophil chemotaxis

12
Q

What stimulates increase in acute phase proteins?

A

IL-6

13
Q

IL-8?

A

Chemotactic factor neutrophils

14
Q

IL-1 another name?

A

osteoclast-activating factor.

15
Q

What inhibits inflammatory response?

A

IL-10 and TGF-ß