T6 Muscles and Nerves Flashcards
(94 cards)
Name a B1 blocker.
Metoprolol
What is atropine used for?
Prevent sinus bradycardia after MI, anticholinesterase poisioning treatment, prevent bradycardia in surgery
What is a twitch vs a tetanus?
A twitch is a brief mechanical response to a single AP, tetanus is sustained mechanical response to a series of APs
Name an B1 selective agonist.
Dobutamine
Where are A1 postsynaptic receptors found?
Smooth muscle
What does the lateral horn of grey matter contain?
Preganglionic autonomic neuron cell bodies
Where are B1 postsynaptic receptors found?
Mainly heart
What are M3 antagonists and botox used to treat?
Overactive bladder
Name a A blocker.
Phenoxybenzamine
Where is acetylcholinesterase located?
Post synaptic membrane
How long does suxamethonium last?
5m
What surrounds single myofibres?
Endomysium
What surrounds a whole muscle?
Epimysium
What would be the effect of blocking ganglionic nicotinic receptors at rest?
Constapation
What would be the effect of blocking ganglionic muscarinic receptors at rest?
Decrease sweating
What is the light part of a striation?
The I band
What do denticulate ligaments do?
Join spinal chord to lateral vertebral walls
How is Ca2+ released to smooth muscle?
From the extracellular space via Ca2+ channels. These are opened by binding of phospholipase 3 to receptors, releasing IP3 which acts on SR which acts on ion channels to cause Ca2+ influx
Which zone only contains myosin?
The H zone
How long is a single twitch?
100-300 ms
How are cardiac muscle cells linked mechanically and electronically?
By desosome and adherens junctions mechanically, by gap junctions electrically (intercalated discs)
Is the vasomotor tone controlled by the sympathetic or parasympathetic nervous system?
Sympathetic
How many motor neurons innervate a motor unit in a whole muscle?
One motor unit is innervated by one motor neuron
Where are autonomic cholinergic receptors located?
In paravertebral ganglia