T7. MOTILITY, ABSORPTION AND SECRETION IN THE COLON Flashcards

(65 cards)

1
Q

Where does the colon begin?

A

At the cecum, just after the ileocecal valve

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2
Q

What attaches to the lower end of the cecum?

A

The appendix

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3
Q

What follows the cecum in the colon?

A

The ascending colon

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4
Q

What colon sections frame the small intestine?

A

Ascending, transverse, and descending colon

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5
Q

What comes after the descending colon?

A

The sigmoid colon

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6
Q

Where does the sigmoid colon lead?

A

Down into the pelvis

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7
Q

What follows the sigmoid colon?

A

The rectum

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8
Q

Where does the large intestine end?

A

At the anal canal and anus

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9
Q

How long is the anal canal?

A

About 3 cm

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10
Q

What happens in the anal canal during defecation?

A

Mucus is released

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11
Q

What does the gross anatomy of the colon include?

A

Cecum, appendix, ascending, transverse, descending, sigmoid colon, rectum, anal canal

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12
Q

Where does the duodenum begin and end?

A

First 25–30 cm, ends at the duodenojejunal flexure

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13
Q

What does the duodenum receive?

A

Stomach contents, pancreatic juice, and bile

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14
Q

What occurs in the duodenum with stomach acid?

A

It is neutralized

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15
Q

What happens to fats in the duodenum?

A

They are emulsified by bile salts

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16
Q

What happens to pepsin in the duodenum?

A

It is inactivated by increased pH

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17
Q

What enzymes take over digestion in the duodenum?

A

Pancreatic enzymes

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18
Q

How much of the small intestine is the jejunum?

A

40% of the postduodenal small intestine

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19
Q

What is the wall of the jejunum like?

A

Thick and muscular

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20
Q

Where does most digestion and absorption occur?

A

In the jejunum

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21
Q

How much of the small intestine is the ileum?

A

60% of the postduodenal small intestine

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22
Q

What are structural characteristics of the ileum?

A

Thinner, less muscular, less vascular

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23
Q

What is the ileocecal junction?

A

Where the ileum joins the cecum of the large intestine

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24
Q

What is the ileocecal valve?

A

A sphincter regulating passage of residue into the large intestine

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25
What muscularis externa structures are found in the colon?
Thick inner circular and thinner outer longitudinal layers
26
What are taenia coli?
Three thickened longitudinal muscle strips in the colon
27
What are haustra?
Pouches caused by taenia coli muscle tone
28
What is the internal anal sphincter made of?
Smooth muscle (muscularis externa)
29
What is the external anal sphincter made of?
Skeletal muscle
30
What increases surface area in mucosa/submucosa of the colon?
Plicae (circular folds)
31
Does the large intestine have villi or circular folds?
No, it lacks both
32
What type of cells are abundant in the colon?
Mucus-secreting goblet cells
33
What does the lamina propria and submucosa contain in the colon?
Large amount of lymphatic tissue
34
What is the purpose of lymphatic tissue in the colon?
Protection from densely populated bacteria
35
What volume of residue does the large intestine receive per day?
About 1.5 L
36
How much residue becomes feces?
Reduced to about 200 mL
37
What vitamins are produced by colon microbes?
Vitamin K and B vitamins
38
What does the colon absorb?
Water, electrolytes, vitamin K, some B vitamins
39
What are feces composed of?
75% water, 25% solids (bacteria, undigested fiber, fat, mucus, epithelial cells)
40
How many species of bacteria live in the colon?
Several hundred species
41
What is a commensal relationship with bacteria?
Bacteria benefit, we are not harmed
42
What is a mutualistic relationship with bacteria?
Both bacteria and host benefit
43
What do microbes produce from cellulose?
Fatty acids
44
What do colon epithelial cells use for energy?
Some fatty acids produced by microbes
45
How do microbes help defend the body?
They compete with harmful bacteria
46
What can disruption of microflora lead to?
Irritable bowel disease
47
Where does most fluid absorption occur?
In the small intestine
48
How much water is left unabsorbed per day?
About 200 mL excreted with feces
49
How is water absorbed in the colon?
Passively via osmotic gradient from Na+/K+ pumps
50
What hormone stimulates salt and water absorption in colon?
Aldosterone
51
How is water secreted in the colon?
By osmosis, due to active Na+ or Cl– transport
52
How long does residue stay in the colon?
12 to 24 hours
53
Does the colon chemically change the residue?
No, it only physically processes it
54
What kind of motility occurs every 30 minutes in the colon?
Haustral contractions (a form of segmentation)
55
What triggers a haustral contraction?
Distension of a haustrum
56
How often do mass movements occur in the colon?
1 to 3 times a day
57
What triggers mass movements in the colon?
Gastrocolic and duodenocolic reflexes
58
What causes the gastrocolic reflex?
Filling of the stomach
59
What causes the duodenocolic reflex?
Filling of the duodenum
60
What happens as material enters the rectum?
Pressure increases due to rectal muscle contraction
61
What does rectal pressure cause?
Relaxation of the internal anal sphincter
62
What controls voluntary defecation?
The external anal sphincter
63
What happens during defecation?
Rectal muscles contract, anal sphincters relax
64
What is the first step in neural control of defecation?
Filling of the rectum
65
What is the second step in neural control of defecation?
Reflex contraction of rectum and relaxation of internal anal sphincter