TC3 Meds

Question 1

Naltrexone

Answer 1

Opiate antagonist (blocks alcohol-induced increases in mesolimbic dopamine release)– used to treat alcohol dependence

Question 2

Methadone

Answer 2

Synthetic opioid (brings pt’s down slowly)– used to treat heroin dependence

Question 3

LAAM

Answer 3

Synthetic opioid (brings pt’s down slowly, longer half-life than methadone)– used to treat heroin dependence

Question 4

Buprenorphine

Answer 4

Mu-receptor partial agonist (similar to methadone, LAAm; less regulated)– used to treat heroin dependence

Question 5

Disulfiram

Answer 5

Acetaldehyde dehydrogenase inhibitor (increases unpleasant symptoms when drinking EtOH)– rarely used to treat EtOH dependence

Question 6

Acamprosate

Answer 6

GABA agonist/glutamate antagonist– used to treat EtOH dependence (effectiveness debated)

Question 7

Bupropion

Answer 7

Dual-action antidepressant (increases dopamine, NE)– used to treat tobacco dependence