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Flashcards in Test 1 Deck (66)
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1

Who concluded that childbed fever resulted from un washed hands:

Iganz Semmelweis

2

What was the principal cause of death at the beginning of the 20th century:

Infectious diseases

3

Who discovered the unseen microbial world

Antony Van Leeuwenhoek

4

Who noted that many diseases were transmitted in a predictable pattern

G. Fracastoro

5

Whos research on rabies led to the development of vaccination

Louis Pasteur

6

This man is accepted as the fater of the Germ Theory of Disease

Robert Koch

7

Who was the first to suggest that disease might be cause by invisible agents transmitted directly, or by fomites, or though the air:

G. Fracastoro

8

THe Prokarya is

No Membrane

9

Of the Eukaryotes, it can be said:

Membrane bound

10

Classification of the three domains of life, prokarya, archae, eukarya, is based on

base sequences RNA segment of ribosomes

11

Concerning the use of the binomial system of taxonomy

Species names always begin with lower case letters

12

What is the glycocalyx and what role does it play in bacteria.

Protection and attachment layer made up of polysaccharides, Slime layer

13

Why are members of the Genera Bacillus and Clostridium so resistant to environmental stress

Because they are bacterial endospores which allows them to be ametabollic and not require any nutrition

14

Bacterial genetics includes HORIZONTAL as well as vertical processes. Name and describe three process of horizontal genetic exchange in bactera.

Conjugation-Transfer of DNA from cell to cell
Transformation-Transfer of naked DNA into cell(cell to enviorment)
Trasduction-DNA from bacteriophage into cell

15

What is POG, and how is it different from plant cell walls

Peptidoglycan, alternating polysaccharide chins. N-acetylyglucosamine and N-acetyimuramicacid linked by peptide. It lets the cell constrict & expand. Thick cell wall

16

What are plasmids:

Self replicating cells that contain DNA

17

What rold do they play in bacterial genetics

They are part of the normal method of replication (Conjugation

18

The Germ Theory of Disease was firmly established when it was conclusively demonstrated that the disease known as Anthrax was cuased by this bacterial species

Bacilius anthriseis

19

What was Edward Jenner's contribution to disease prevention:

He developed the idea of vaccination and was able to prove it worked, used milk maids to prevent small pox

20

GIve examples of the non-specific immunologic barriers to infection

Anatomic-SKin
Physiologic-Temp and pH
Endocytic- Cells inside body, Keep bacteria outside
Inflammatory- "redness and swelling with Heat and Pain"

21

What is meant by "normal Flora"

A bacteria that is helpful or common to the body

22

How is "normal FLora a protective barrier of disease

It helps to crowd out the harmful bacteria

23

Where is "normal flora" located

Skin, mucous membranes, gut

24

Name three characteristic of the epidermis that make it and effective barrier to infection

Salty surface, Frequent dequimation, No blood vessels, dry, acidic

25

What is Koch's first postulate

Infected tissue must show presence of particular microoganism not found in healthy animals

26

What is Koch's second postulate

Microorganism must be isolated & grow in pure culture

27

What is Kroch's 3rd postulate

When injected into healthy animal, microorganism must cause associated disease

28

What is Kroch's 4th postulate

"second generation" microorganism should be isolated & be identical to the first.

29

What characteristic of Gram-negative bacteria make all of them potentially pathogenic

The lipopolysaccharide molecules on the cell that secreate Lipase A which makes TNF causeing sickness

30

What are the three different clinical diseases in humans that Anthrax can cause

Cutaneous Anthrax
Intestinal Anthrax
Pulmonary Anthrax