Test 4 muscle relaxant shi Flashcards
(10 cards)
Centrally Acting skeletal Muscle Relaxant therapuetic action
Work in CNS to interfere w reflexes causing muscle spasm
Indications of centrally acting skeletal muscle relaxants
Relief of discomfort associated with acute painful musculoskeletal conditions
Adjunct to rest, physical, and occupational therapy
Most common prescription muscle relaxers?
Baclofen (antispasticity)
Benzodiazapines
Carisoprodol (antispasmodic)
Chlorzoxazone (antispasmodic)
Cyclobenzaprine(antispasmodic)
Dantrolene (antispasticity)
Metaxalone (antispasmodic)
Methocarbamol (antispasmodic)
Orphenadrine (antispasmotic)
Tizanidine (both)
Contraindications/ cautions of centrally acting skeletal muscle relaxants
Spasms from rheumatic disorders
Epilepsy
Cardiac dysfx
Conditions marked by muscle weakness
Preg/lact
Adverse effects of centrally acting skeletal muscle relaxants
CNS depression
GI
Hypotension and arrhythmias
Orthostatic Hypo
Urinary frequency, enuresis, urinary urgency
Chlorzoxazone can discolor urine
Tizanidine associated with liver tox in some pt’s
Direct acting skeletal muscle relaxants contraindications
Dantrolene: Spasticity that contributes to locomotion
Upright position
Increased fx
Active hepatic disease
Cautions of direct acting skeletal muscle relaxants
Female pt’s
Age over 35
History of liver disease or previous dysfx
Resp depression
cardiac arrest
Adverse effects of direct acting skeletal muscle relaxants
Dantrolene: CNS depression, GI, hepatocellular damage, hepatitis
Botulinum toxins: Anaphylactic reactions, headaches, muscle pain, paralysis,
What should you monitor for when pt is taking baclofen?
Abrupt discontinuation can cause seizures
What should you monitor for when pt is taking cyclobenzaprine?
Can cause seratonin sydndrome when combined with SSRI or SNRI
