Test 5 Hypothalamic and Pituitary agents shi Flashcards
(16 cards)
Desmopressin
Mimics ADH to increase water reabsorption in the kidneys , treating diabetes insipidus
Decreases urine ouput
Octreotide
Reduces release of growth hormone which is excessive in acromagely, helping to control coarse facial features splayed teeth, and large hands and feet
Treats Upper GI bleed too
When given PO, give on empty stomach with ass of water
Gonadotropins
Used to induce ovulation and pregnancy in women who are anovulatory
Somatropin
Recombinant human GH used to help treat children with GH deficiency to promote skeletal growth
Monitor a child growth rate and bone age
Stop treatment prior to epiphyseal closure
Examples of glucocorticoids
Cortisone
Prednisone
-sone
-lone
What do glucocorticoids do?
Stimulate increase in glucose levels for energy
Suppress inflammatory responses and immune response
Cautions and contraindications of glucocorticoids
Acute infeciton not controlled by antibiotics
Diabetes
Acute peptic ulcers
Pregnancy and lactation
Adverse effects of glucocorticoids
Children: Risk for diminished growth
Systemic adverse effects
Adrenal insufficiency
Behavioral and mood disturbances
Drug interactions of glucocorticoids
NSAIDS
Alc
Potassium depleting agents
Vaccines
Anticoags
What are the 6 S of steroids?
Sugar (hyperglycemia)
Soggy Bones (osteoperosis)
Sick (Decreased Immunity)
Sad (depression)
Salt (salt and water retention)
Sex (decreased libido)
Mnemonic for steroid side effects
HIGGGH HOMIE
HTN
Immunosuppression
Go crazy
Glaucoma
Growth Retardation
Hyperglycemia
Hair growth (hirsutism)
Osteoperosis
Muscle Weakness
Increased Appetite (gain weight)
Edema
What insulin is best to use for steroid induced hyperglycemia?
For steroid induced hyperglycemia it’s best to use an NPH insulin to treat
Somatropin Side effects
Hyperglycemia
Pancreatitis
Rotate injection sites
Desmopressin side effects
Overhydration : Pounding headache
What should we teach patients when taking glucocorticoids?
Don’t stop taking them suddenly
Taper the drug slowly
Take vitamin D and supplements
Avoid NSAIDS
Fludrocortisone
Treats Addison’s disease
Mimics aldosterone
Reabsortption of salt and water at the kidneys ; maintains BP and sodium balance
Side effects: HTN, Edema, Hypokalemia, hyperglycemia, adrenal gland suppression
Don’t abruptly discontinue this med because it can cause addisonian crisis
