The genetic explanation Flashcards

(13 cards)

1
Q

What are the three genetic explanations?

A

Family, twin and adoption studies

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2
Q

What does the genetic explanation believe?

A

The closer the biological relationship, the increased risk of schizophrenia developing

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3
Q

Why are family twin and adoption studies used?

A

Establish how strong a genetic link is

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4
Q

What did the family study by kety et al find?

A

207 high risk children, mothers had schizophrenia- 16.2% diagnosed
104 low risk children, health mothers- 1.9% diagnosed

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5
Q

What did the family study by kendler et al find?

A

1st degree relatives of those with schizophrenia are 18 times more at risk (genetic link, risk increases with closer genetic relationship)

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6
Q

What did the family study by gottesmean find?

A

48% risk in identical
17% risk in fraternal

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7
Q

What is a criticism of family studies?

A

63% diagnosed have no family history, suggests other factors might be involved

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8
Q

What did the twin study by Gottesman and Shields find?

A

Concordance of 42% for identical and 9% for fraternal

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9
Q

What did the twin study by Torey find?

A

Reassessed 8 studies, concordance 26% for identical, 9% for fraternal

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10
Q

What did the twin study by cardno et al find

A

Concordance of 40% for identical and 5.3% for fraternal

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11
Q

What did the adoption study by Heston find?

A

47 children with schizophrenic mothers dopted at 1 month, 10 developed, non of the control developed

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12
Q

What did the adoption study by tiener et al find?

A

112 adopted biological mum diagnosed, 135 adopted biological mum not diagnosed, 7% of 112 developed, 1.5% of 135 developed

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13
Q

Evaluation of twin?

A

The genetic relatedness of identical would lead to high concordance rate should be similar but they arent. Suggests other factors involved

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