The TCA cycle Flashcards
where does the TCA cycle take place
the mitochondria
what pathways happen before the TCA
Electron transport chain and oxidative phosphorylation
what condenses to form Citrate (6C)
acetate (2C) and oxaloacetate (4C)
what else is produced from the TCA apart from citrate
CO2, GTP, NADH and FADH2. oxaloacetate is also regenerated
each acetyl CoA that turns the cycle produces what
3 NADH, 1 FADH2, 1 GTP, 2 CO2
what is the first chemical compound in the cycle
acetyl CoA
where do the 2 NADH that are produced go
Electron Transport Chain
where does the 1 FADH2 produced go
Electron Transport Chain
where does the 1 GTP produced go
becomes ATP
where does the 2 CO2 produced go
waste
explain the role of succinate Q-reductase
an enzyme that converts succinate to fumarate
where is succinate Q-reductase
embedded in the inner mitochondrial membrane
for each acetyl CoA that turns the TCA cycle how many ATP does it theoretically produce
12
what makes up the 12 theoretically produced ATP from the TCA Cycle
GTP = 1ATP
3 NADH = 9 ATP
FADH2 = 2 ATP
what is linked to the energy status, in terms of the regulation of the TCA cycle
isocitrate dehydrogenase activity
