things that increase/decrease MAC Flashcards
(43 cards)
1
Q
MAC definition
A
the partial pressure of an inhalation anesthetic at 1 atmosphere that prevents skeletal muscle movement in response to surgical skin incision in 50% of the population
2
Q
The lower the MAC, the more ___ the agent, and the ___ the blood:gas partition coefficient
A
potent, higher
3
Q
hypoxia
A
decrease
4
Q
infants
A
increase
5
Q
MAC usually greatest in
A
newborn
6
Q
anemia
A
decrease
7
Q
hyperthermia
A
increase
8
Q
lithium
A
decrease
9
Q
chronic alcohol and drug use
A
increase
10
Q
sedatives
A
decrease
11
Q
red heads
A
increase
12
Q
pregnancy
A
decrease
13
Q
hypothermia
A
decrease
14
Q
hypotension
A
decrease
15
Q
hyperthermia if >42C
A
decrease
16
Q
decreased PAO2
A
decrease
17
Q
hematocrit <10%
A
decrease
18
Q
decreased MAP
A
decrease
19
Q
PAO2 >95mmHG
A
decreased caused by
20
Q
elderly
A
decrease
21
Q
thyroid
A
no change
22
Q
CCB’s
A
decrease
23
Q
acute ETOH ingestion
A
decrease
24
Q
hypercalcemia
A
decrease
25
decreased CBF
decrease
26
decreased CMRO2
decrease
27
hypernatremia
increase
28
hyponatremia
decrease
29
local anesthetics
decrease
30
cocaine as a local anesthetic
increase
31
sympathomimetic drugs (cocaine,ephedrine, amphetamine)
increase
32
chronic amphetamine
decrease
33
levodopa
increase (apex)
34
lidocaine
decrease (apex)
35
alpha 2 agonists
decrease(apex)
36
cardiopulmonary bypass
decrease(apex)
37
hypo-osmolarity
decrease (apex)
38
metabolic acidosis
decrease (apex)
39
hyperkalemia
does not affect! (apex)
40
hypokalemia
does not affect! (apex)
41
hypermagnesemia
does not affect! (apex)
42
hypomagnesemia
does not affect! (apex)
43
hypertension
does not affect! (apex)
