Levothyroxin
Treat hypothyroidism
Propylthiouracil (PTU)
Inhibit iodination of tyrosin , coupling of iodotyrosin
Also inhibit T4===>T3 at periphery
Safe in pregnancy woman,
hepatotoxic
Carbimazole
Methmazole
Inhibit iodination of tyrosin , coupling of iodotyrosin
Faster than PTU , less hepatotoxic drug