Tissues of the Immune System Flashcards
(25 cards)
What is the lymphatic system connected to?
circulatory system, spleen, bone marrow
where does lymph originate
blood plasma
interstitial fluid
cleans and nourishes tissues
collects cellular debris and bacteria
returns to lymph capillaries
where do capillaries enter
tissue
where do the veins enters
into circulation
lymph
filtered by lymph node before recirculating
what does lymph become once it starts recirculating
serum or plasma
what are the two classes of lymphoid organs
primary and secondary
what organs are considered primary lymphoid organs
spleen, thymus, bone marrow
what are some of the encapsulated secondary lymphoid organs
lymph nodes, bone marrow, spleen
what are the nonecapsulated or diffuse secondary lymphoid organs
BALTs, GALTs, tonsils, lymphoid nodules
what is the purpose of the primary lymphoid tissue
create, generate, and educate adaptive immune cells like B cells and T cells
What is the purpose of secondary lymphoid tissue
they are in charge of surveillance, recruitment, and act as a home base for all immune cells
what role does the spleen play as a secondary lymphoid organ
filters blood
activates and deactivates lymphocyte activity
removes pathogens
d B cells and T cells mix together in an organ
no!! they each have their own distinct zones and signals or pathways to get them to those zones
is GALT secondary or primary? encapsulated or diffuse
secondary, diffuse
what is the role of dendritic cells
look for danger signals
sample the environment by reaching out into the cell periphery
M cells
bring lymph into the GALT area and assess the fluid
how to T cells get to the T cell zone
high endothelial venules
what are 4 antigen presenting cells
mast cells
dendritic cells
b cells
macrophages
what is the purpose of lymphocyte recirculation
increase the chances for a successful encounter between lymphocyte and pathogen
how do lymphocytes migrate
altering receptor expression and it stops when it experiences a high affinity interaction
bent conformation of a lymphocyte is (low or high affinity) while extended conformation confers a (low or high affinity)
low, high
how does a lymphocyte switch from low to high affintiy
using receptors that are sensitive to chemokine and then binding to ICAM
