Flashcards in Toxicology Deck (18):
what are signs of ibuprofen intoxication?
vomiting and GI haemorrhage
what is the toxic dose of ibuprofen for renal system?
what is the difference between 1st and 2nd gen coumarins
2nd gen are more potent with longer half life
how would you diagnose coumarin poisoning
prolonged cpagulation time - PT and APTT
what substance in chocolate is toxic to dogs?
methylxanthines - theobromine
what are signs of chocolate poisoning in dogs
CNS stimulation and respiratory affects - tachycardia, arrhythmia, seizures, vomiting and abdominal pain
why are cats susceptable to paracetamol poisoning
lack the glucoronidation pathway with detoxifies it in the liver
what would you see in the blood of a cat with paracetamol poisoning
what are the clinical sigsn of paracetamol poisoning in cats
methaemaglobinaemia dysponea, cyanosis , hypothermia and brown mucous membranes
what are the signs of paracetamol poisoning in dogs
hepatic failure - oxidative stress to hepatocytes
what is permethrin found in
signs of permethrin poisoning in cats
hypersalivation, vomiting, ataxia and seizures
what are metaldyhydes
signs of metaldehyde poisoning
anxiety, hyperaesthesia, salivation, tremors, ataxia and tachycardia
what body system do lillies affect in cats
nephrotoxicity - renal failure
what is benzalkonium chloride found in and what are clinical signs of poisoning
tongue ulceration, skin irritation and salivation
what is ethylene glycol and what is used as an antidote?
antifreeze and screen washer - use alcohol