Trans - Gene Expression Flashcards Preview

[OS 201] 3rd Exam > Trans - Gene Expression > Flashcards

Flashcards in Trans - Gene Expression Deck (86)
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1

retroviruses

RNA viruses that make DNA copies of themselves by using reverse transcriptase

2

reverse transcriptase

enzyme that creates DNA from RNA template

3

retrotransposons

sequences of DNA that make RNA copies of themselve, then get reverse-transcribed into DNA

4

operons - type/level of control

transcriptional control

5

operons

functioning unit of genomic DNA containing a cluster of genes under the control of a single regulatory signal or promoter

6

enzyme for transcription

RNA polymerase

7

subunits of RNA polymerase [5]

[1] alpha1
[2] alpha2
[3] beta'
[4] beta
[5] omege

8

alpha1 subunit of RNA polymerase

assembling of RNA polymerase complex

9

alpha2 subunit of RNA polymerase

assembling of RNA polymerase complex

10

beta' subunit of RNA polymerase

template binding

11

beta subunit of RNA polymerase

catalytic subunit for RNA synthesis

12

enzyme catalyzed by beta subunit of RNA polymerase

5' --> 3' polymerase

13

omega subunit of RNA polymerase

unclear function

14

subunits of eukaryotic RNA polymerase

2 alpha, 2 beta, omega, 7 more

15

RNA polymerase I

synthesis of rRNA (28S, 18S, 5.8S)

16

RNA polymerase II

synthesis of mRNA

17

RNA polymerase III

synthesis of tRNA, snRNA, 5S rRNA, misc RNAs

18

raw materials for new RNA

ATP, CTP, GTP, UTP

19

direction of transcription

5'-->3'

20

processes involved in transcription

initiation, elongation, termination

21

relationship of chromatin structure to gene expression

open chromatin --> increased gene expression

22

transcription unit

transcribed segment of DNA

23

promoter regions [3]

[1] TATA box
[2] CAAT box
[3] GC box

24

classes of transcription factors [3]

[1] basal components
[2] activators
[3] corregulators

25

basal components

allow transcription to take place at lower levels

26

examples of basal components

TBP, TFIIA, B, E, F, H

27

activators

bind to distal regulatory elements - enhancers

28

corregulators

bind to distal regulatory elements - enhancers

29

examples of activators

TFIID

30

examples of corregulators

SP1, atf, ctf, ap1