Transport across membranes Flashcards

(33 cards)

1
Q

What does the plasma membrane define

A

borders of cells and most organelles

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2
Q

How permeable is the membrane

A

Partially permeable

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3
Q

What does it mean if the membrane is partially permeable

A

the membrane allows some materials to freely enter or leave the cell/organelle while other materials cannot move freely

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4
Q

What does a phospholipid molecule consist of

A
  • glycerol
  • 2 fatty acids
  • phosphate-linked head group
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5
Q

What’s the thickness of a phospholipid

A

5-10nm in thickness

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6
Q

Where does the hydrophilic phospholipid head face

A

outwards and the hydrophobic fatty acids faces inwards

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7
Q

What is cholesterol

A

A lipid that sits with phospholipids in the core of the membrane

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8
Q

Where is cholesterol not found

A

in bacterial cell membranes

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9
Q

What affect do cholesterol molecules have on the membrane

A

makes it more rigid

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10
Q

What does cholesterol help maintain

A

Shape of animal cells

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11
Q

What does the phospholipid bilayer form

A

the ‘fluid’ part of the ‘fluid mosaic’ model

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12
Q

What’s the ‘mosaic’ part made up of

A

various proteins, carbohydrates and lipid molecules that punctuate membranes

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13
Q

What’re membrane bound molecules

A

Large molecules embedded in the bilayer

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14
Q

What can the bilayer form

A

open pores

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15
Q

What do open pores allow

A
  • diffusion of large molecules across the bilayer

- transport proteins that bind to specific molecules and carry them across the membrane

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16
Q

What does the glycolipid act as

A

A recognition site for toxins

17
Q

On the plasma membrane what part points outwards

A

hydrophilic heads of phospholipid molecules

18
Q

What part of the membrane points inwards

A

The hydrophobic part

19
Q

What do the glycoproteins do in the plasma membrane

A

branching carb of a protein which acts as a recognition site for chemicals

20
Q

What’s cholesterol needed for in the cell membrane

A

stability and flexibility

21
Q

What’re the 2 proteins found in the membrane

A
  • intrinsic

- extrinsic

22
Q

What’re 2 examples of intrinsic proteins

A
  • channel proteins

- carrier proteins

23
Q

What do channel proteins provide

A

hydrophilic channel that allows the passive movement of polar molecules and ions

24
Q

What holds channel proteins in place

A

interactions between hydrophobic core of the membrane and hydrophobic R-groups on the outside

25
What do carrier proteins have an important role in
both passive transport and active transport into cells
26
What do carrier proteins affect
shape of the protein changing
27
What type of proteins are glycoproteins
Intrinsic proteins
28
Where is the glycoprotein located
cell surface membrane with attached carb chains of various length and shape
29
What do glycoproteins play the role in
cell adhesion and as receptor for chemical signals
30
What's cell signalling
when chemicals bind to the receptor causing a response from the cell which sets of a cascade of events inside the cell
31
What're 2 examples from cell signalling
- receptors for neurotransmitters (acetylcholine at nerves) | - Receptors for peptide hormones (insulin and glucagon
32
What're glycolipids
lipids with attached carbohydrate chains
33
What're glycolipids known as
cell markers or antigens and can be recognised by cells of the immune system