Trigger - prostate disorders Flashcards

1
Q

risk factors for this condition includes catheters, prostate biopsy, urethral stricture

A

acute bacterial prostatitis

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2
Q

DRE showing red hot tender prostate

A

acute bacterial prostatitis

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3
Q

leukocytosis showing left shift. UA showing pyuria, bacteriuria, hematuria. UC - + causative agent.

A

acute bacterial prostatitis

remember you have to get a culture in these patients so you can use the right abx

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4
Q

in acute bacterial prostatitis, if there is no response to abx in 24-48 hrs what should be done

A

pelvic CT or transurethral US to assess for abscess

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5
Q

treatment is amp/gent or fluoroquinolones +/- aminoglycoside

A

acute bacterial prostatitis that is NOT nosocomial

quinolones - cipro/levo/moxi
aminoglycosides ex- gentamicin, tobramycin, streptomycin

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6
Q

treatment includes carbapenem, broad spectrum PCN +/- aminoglycoside, broad spectrum ceph +/- aminoglycoside

A

nosocomial acute bacterial prostatitis

ceph - cefdinir, cefipime
pcn - ampicillin

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7
Q

treatment includes bactrim, levo, cipro.

A

oral abx tx for acute bacterial prostatitis

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8
Q

pain that is dull, poorly located, in suprapubic, perineal or low back regions.

A

chronic bacterial prostatitis

this could also be in nonbacterial prostatitis, CPPS

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9
Q

DRE showing boggy/spongy, tender, enlarged and/or indurated prostate

A

chronic bacterial prostatitis

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10
Q

positive urine culture AFTER prostatic massage

A

chronic bacterial prostatitis

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11
Q

lipid laden macrophages and WBCs in prostate secretions

A

chronic bacterial prostatitis

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12
Q

flouroquinolones or bactrim is used in treatment of what

A

chronic bacterial prostatitis

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13
Q

all negative tests except perhaps WBCs on the prostatic secretions MAYBE

A

nonbacterial prostatitis or CPPS

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14
Q

treated with 5-a reductase inhibitors

A

nonbacterial prostatitis or CPPS

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15
Q

which alpha blockers are used for urinary symptoms that have less SE?

A

tamsulosin
sildosin
alfuzosin

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16
Q

this medication causes relaxation in bladder neck and smooth muscle in the prostate

A

alpha blockers (tamsulosin, sildosin, alfuzosin)

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17
Q

not recommended in young men d/t decreased semen volume

A

5-a-reductase inhibitors
finasteride
dutasteride

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18
Q

what parts of the prostate are increased in BPH

A

glandular and stromal components

19
Q

presents with mainly obstructive voiding that is slow onset and gradually progresses

A

BPH

20
Q

hypertrophy, hyperplasia and collagen deposition are the causes of what

A

BPH irritative voiding s/s

21
Q

DRE showing smooth, firm, symmetric, elastic enlargement of prostate

A

BPH

22
Q

induration or assymetric enlargement of prostate

A

cancer

23
Q

normal UA, may see slight elevation in PSA

A

BPH

24
Q

when is US indicated in BPH

A

high serum Cr or UTI

25
Q

watchful waiting indicated when

A

mild BPH = AUA score of 0-7

26
Q

SE for orthostatic hypotension, dizziness, and floppy iris syndrome

A

alpha 1 blockers

27
Q

DDI with antihypertensives and PDE-5 inhibitors

A

alpha blockers

28
Q

converts testosterone to dihydrotestosterone

A

5-4-redutase inhibitor

29
Q

takes 6 months to see the full benefits of this drug

A

5-a-reductase inhibitors

30
Q

reduces prostate side by 20%

A

5-a-reductase inhibitors

31
Q

SE decreased libido and erectile/ejaculatory dysfunction

A

SE of 5-a-rductase inhibitors

32
Q

what is the affect of NSAIDS, smoking and ETOH on risk of BPH

A

decreases risk of developement

33
Q

if a patient has gross hematuria or recurrent UTIs how would it affect their treatment plan for BPH

A

they would NOT be a candidate for watchful waiting

also not a candidiate:
- refractory urinary retention
- large bladder diverticula
- bladder stones
- CKD

34
Q

MC used surgical tx for BPH

A

TURP

35
Q

pt after surgery has complaints of HTN, confusion, NV, and seiuzres

A

transurethral resection syndrome

also see:
bradycardia
coma
visual disturbances
spasms

36
Q

what sugircal intervention is used if the prostate is over 100 grams

A

open/robotic simple prostatectomy

37
Q

which minimally invasive prostate treatments use heat to treat BPH

A
  • TULIP (i guess cuz technically its a laser)
  • TU - electrovaporization
  • TUNA (radiofrequency waves)
  • hyperthermia
  • rezume (vapor thermal treatment)
38
Q

a patient presents with obstructive voiding s/s and hx of multiple vertebral fractures

A

probs prostate cancer

39
Q

elevated alk phos/hypercalcemia

A

bony metastases in prostate cancer

40
Q

a patient has prostate cancer that is confined to the prostate and is palpable on exam. what stage is it?

A

stage T2

reminder:
T1 - Clinically inapparent (not seen on imaging or palpated
on exam) - elevated PSA only
T2 - Tumor confined within prostate, visible or palpable
T3 - Tumor extends through prostate capsule, may invade seminal vesicles
T4 - Tumor is fixed or invades adjacent structures

41
Q

removal of seminal vesicles, ampulla of vas deferens and the prostate is known as what

A

radical prostatectomy

42
Q

glycoprotein produced only by cells of the prostate gland

A

PSA

43
Q

when should you discontinue DRE and PSA screening

A
  • PSA <1.0 at age 65
  • PSA <3.0 at age 75
  • Life expectancy < 10 years
44
Q

thiazides, statins, NSAIDS and 5-a reductase inhibitors all have this in common

A

they all reduce PSA!!!!!!