Tumors Flashcards

1
Q

who usually gets an osteois osteoma?

A

young patients

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2
Q

when does pain really get bad with osteoid osteoma?

A

at night

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3
Q

what can really help osteiod osteoma?

A

NSAIDs

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4
Q

what can exacerbate osteoid osteoma?

A

alcohol

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5
Q

are osteiod osteomas usually biopsied?

A

no

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6
Q

who usually gets osteosarcoma?

A

young…ages 5-25

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7
Q

if older person gets osteosarcoma what can it be secondary to?

A

paget disease or prior radiation

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8
Q

where does osteosarcoma occur in the bone?

A

metaphyseal

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9
Q

what is the buzz word for how osteosarcoma looks?

A

sunburst

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10
Q

what is treatment for osteosarcoma?

A

systemic chemo with surgical resection

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11
Q

when do you have pain with osteosarcoma?

A

at night and at rest

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12
Q

what is histo pattern of osteosarcoma?

A

atypical cells producing osteoid

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13
Q

what can be associated with osteosarcoma?

A

retinoblastoma

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14
Q

what age gets osteochondroma?

A

young under 20

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15
Q

what is classic presentation of osteochondroma?

A

fixed mass that is painless in child

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16
Q

where doe osteochondroma grow?

A

grows away from metaphyseal

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17
Q

is there pain with osteochondroma?

A

no, unless its tendonitis or bursitis

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18
Q

what is the genetic disorder with osteochondroma

A

AD..multiple osteochondromas

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19
Q

what does osteochondroma look like on histo?

A

looks like a growth plate

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20
Q

who gets enchodromas?

A

over 30 yrs old

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21
Q

where do enchodromas grow?

A

metaphyseal, central in bone

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22
Q

what is a common anatomic location for enchodromas?

A

hand

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23
Q

is there pain with enchodromas?

A

no

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24
Q

how are enchodromas found?

A

often on accident

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25
chondrosarcomas is in what ages?
50 and above
26
are chondrosarcomas more concerning when distal or proximal?
proximal
27
how do chondrosarcomas appear on Xray
stippled pattern suggesting cartilage
28
how does chondrosarcomas appear on histo?
more cellular than enchondroma, considerable atypia
29
what is classic presentation for chondrosarcomas ?
older patient with enlarging hip/pelvis/shoulder mass
30
what is a simple/unicameral bone cyst?
small single bone cyst usually found at proximal humerus or femur
31
name two common locations for simple/unicameral bone cyst
femur/humerus
32
what age gets simple/unicameral bone cyst?
under 20
33
is there pain with simple/unicameral bone cyst?
nah not usually
34
what is a nonossifying fibroma?
self limiting osseous lesion
35
where do you see nonossifying fibroma in bone?
metaphyseal
36
what age gets nonossifying fibroma?
under 20
37
how do nonossifying fibroma appear on Xray?
lucent with lobulated bubbly look
38
how does fibrous dysplasia appear on Xray?
ground glass appearance
39
when does fibrous dysplasia usually present?
childhood
40
what are the two types of fibrous dysplasia?
monostotic | polystotic
41
what can polyostotic fibrous dysplasia be associated with?
Mccune Albright syndrome
42
how does fibrous dysplasia appear on histo?
immature bony trabeculae with bland fibrous stroma (alphabet soup)
43
where do giant cell tumors occur in bone?
epiphysis of long bones
44
is giant cell tumor lucent or opaque on Xray?
lucent
45
what do you see a lot of with giant cell tumor on histo?
giant cells
46
if you get a lesion in epiphyses of bone..what is it?
giant cell tumor
47
where does ewing sarcoma occur in bone?
diaphysis
48
how does ewing sarcoma appear on xray?
onion skinning on Xray
49
what can ewing sarcoma be associated with? so what can it be confused with?
fever and ESR...osteomyelitis
50
how does ewing sarcoma appear on histo?
small round monomorphic cells
51
what is typical translocation of ewing sarcoma?
11 and 22
52
what are the two pediatric osseous malignancies?
osteosarcoma and ewing sarcoma
53
new bony lesion in patient older than 50 think what three things?
metastatic disease myeloma lymphoma
54
if it is a primary tumor in someone older than 50...what two things do we think?
chondrosarcoma or secondary osteosarcoma
55
how does MM appear on Xray?
multifocal and radiolucent
56
what is a common site for test questions to ask about MM?
skull lesions
57
what are five common primary cancers that spread to bone?
``` lung breast prostate renal thyroid ```
58
what does myositis ossificans cause in bone?
tumor stimulator
59
what can myositis ossificans cause to form in muscle?
hetertropic bone
60
what is a common location for myositis ossificans?
quad
61
how does myositis ossificans appear on Xray?
outer rim is opaque and inner area is lucent
62
why does outer area of myositis ossificans appear more opaque?
because the bone matures from outside to in
63
how does myositis ossificans usually present?
young patient with trauma to leg and a developing mass after trauma
64
is myositis ossificans painful?
not usually
65
what can paget disease contribute to?
tumor contributor/stimulator
66
what is paget disease associated with?
osteosarcoma
67
what other organ system is problem in paget disease?
endocrine
68
who gets paget disease?
older patients more than 50yo
69
is paget disease painful?
yes
70
what can you see happen to bones in paget disease?
bone bowing