Tumour classification Flashcards Preview

Year 2 EMS MoD > Tumour classification > Flashcards

Flashcards in Tumour classification Deck (59):
1

What is the role of surface epithelia?

Protection

2

What is the role of glandular epithelia?

Secretion (glands and ducts)

3

What is the name for a benign tumour of surface (non glandular/non secretory) epithelium?

Papilloma

4

What is the name for a benign tumour of glandular (secretory) epithelium?

Adenoma

5

Benign tumours of surface epithelium are further identified by what?

Name of cell type of origin eg. squamous cell

6

Benign tumours of glandular/secretory epithelium are further identified by what?

Name of glandular tissue of origin

7

What would a benign tumour of squamous surface epithelium be called?

Squamous cell papilloma

8

What would a benign tumour of ductal epithelium of the pancreas be called?

Pancreatic cystadenoma

9

What are the 4 exceptions to the nomenclature rules for benign epithelial tumours?

1) Melanoma
2) Lymphoma
3) Seminoma
4) Mesothelioma

10

What are malignant epithelial tumours called?

Carcinomas

11

How are malignant tumours of surface epithelium named?

Prefixing carcinoma with the cell of origin eg. squamous cell carcinoma

12

How are malignant epithelial tumours derived from glandular/ductal epithelium named?

Prefixing adenocarcinoma with the epithelium source eg. pancreatic adenocarcinoma

13

What is important to note when naming epithelial malignant tumours?

Reference is often made to the degree of differentiation in epithelial malignant tumours eg. moderately differentiated adenocarcinoma

14

What would a benign epithelial tumour of stratified squamous epithelium be called?

Squamous cell papilloma

15

What would a benign epithelial tumour of basal cells of the skin be called?

Basal cell papilloma

16

What would a benign epithelial tumour of transitional epithelium of the bladder be called?

Transitional cell papilloma

17

What would a benign epithelial tumour of the glandular epithelium of the liver be called?

Liver cell adenoma

18

What would a benign epithelial tumour of the glandular epithelium of the thyroid be called?

Follicular adenoma (as talking about thyroid follicles)

19

What would a malignant epithelial tumour of stratified squamous epithelium be called?

squamous cell carcinoma

20

What would a malignant epithelial tumour of basal cells of the skin be called?

basal cell carcinoma

21

What would a malignant epithelial tumour of transitional epithelium of the bladder be called?

Transitional cell carcinoma

22

What would a malignant epithelial tumour of the glandular epithelium of the colon be called?

colonic adenocarcinoma

23

What would a malignant epithelial tumour of the glandular epithelium of the breast be called?

breast adenocarcinoma

24

How are mesenchymal tumours named?

Tissue or cell of origin followed by -OMA

25

What would a benign tumour of bone be called?

Osteoma

26

What would a benign tumour of adipose tissue be called?

Lipoma

27

What would a benign tumour of smooth muscle be called?

Leiomyoma

28

What would a benign tumour of skeletal muscle be called?

Rhabdomyoma

29

What would a benign tumour of a blood vessel be called?

Angioma / Haemangioma

30

What would a benign tumour of cartilage be called?

Chondroma

31

What would a benign tumour of fibrous tissue be called?

Fibroma

32

How are malignant mesenchymal tissues named?

Cell or tissue of origin followed by SARCOMA

33

What would a malignant tumour of bone be called?

osteosarcoma

34

What would a malignant tumour of skeletal muscle be called?

Rhabdomyosarcoma

35

What would a malignant tumour of smooth muscle be called?

Leiomyosarcoma

36

What would a malignant tumour of blood vessels be called?

Angiosarcoma

37

What would a malignant tumour of cartilage be called?

Chondrosarcoma

38

What would a malignant tumour of adipose tissue be called?

Liposarcoma

39

What would a malignant tumour of fibrous tissue be called?

Fibrosarcoma

40

What is a benign tumour of melanocytes called?

Melanocytic Nevus

41

What is a malignant tumour of melanocytes called?

Melanoma

42

What are the possible names for a malignant tumour of blood cells? 3

Leukaemia
Lymphoma
Myeloma

43

What is a tumour of the meninges called?

Meningioma

44

What is a tumour of astrocytes called?

Astrocytoma (Glioblastoma multiforme is from a type of astrocyte)

45

Name 5 types of CNS tumours?

1) Meningioma
2) Astrocytoma
3) Oligoendroglioma
4) Ependymoma
5) Medulloblastoma

46

How are CNS tumours graded?

WHO grading I to IV

47

Germ cell tumours are common in what organs?

Gonads

48

What are seminomatous tumours called?

Seminoma

49

What is a teratoma?

A non-seminomatous germ cell tumour
teeth/hair/muscle/neural/cartilage

50

Who do embryonal tumours occur in?

Occurs in very young,

51

Name 4 kind of embryonal tumours?

1) Retinoblastoma
2) Nephroblastoma (Wilms)
3) Neuroblastoma
4) Hepatoblastoma

52

What are embryonal tumours?

Tumours with histological resemblance to embryonic cells of that organ

53

Is a pleomorphic salivary adenoma benign or malignant?

Benign

54

What is a carcinosarcoma?

Malignant tumour with carcinomatous and sarcomatous components

55

Name 4 malignant tumours with benign names?

1) Melanoma
2) Mesothelioma
3) Myeloma
4) Lymphoma

56

What is a hamartoma?

non-neoplastic overgrowth of normal tissue which is indigenous to the sight of origin (different to choristoma!)
A tumour like lesion which exhibits uncoordinated growth, usually benign and consist of atleast 2 mature cell types normally found in the tissue of the organ in which the lesion lies eg. lung harmatoma contains cartilage and bronchial epithelium

57

What are harmatomas associated with?

Developmental abnormalities

58

What is a choristoma?

Nodules of non-neoplastic organ parenchyma in another organ eg. normal (non neoplastic) pancreas nodule in stomach

59

Why are harmatomas clinically relevant?

They can be mistaken for neoplasms on imaging and can be associated with genetic syndromes eg. tuberous sclerosis