Flashcards in Tumour Pathology Deck (62)
What 2 things does the classification of tumours depend on?
- Region found
- Benign or malignant
What is the name given to benign glandular tumours?
What is the name given to malignant glandular tumours?
What is the name given to benign squamous tumours?
What is the name given to malignant tumours?
What is the name given to benign bone tumours?
What is the name given to malignant bone tumours?
What is the name given to benign fat tumours?
What is the name given to malignant fat tumours?
What is the name given to benign fibrous tissue tumours?
What is the name given to malignant fibrous tissue tumours?
What is the name given to malignant white blood cell tumours?
What is the name given to malignant lymphoid tissue tumours?
What is the name given to germ cell tumours?
Which teratomas are usually benign?
Which teratomas are usually malignant?
What is the difference in growth pattern between benign and malignant tumours?
Benign = non invasive
Malignant = invasive
What differs with regards to the capsule in benign and malignant tumours?
- Benign have an intact capsule
- Malignant have no capsule/capsule breached
Whats the difference between cell functionality of malignant and benign tumours?
Benign = similar to normal cells
Malignant = lost function
What are the 4 properties of cancer cells? (AG AC AF I)
- Altered genetics
- Altered cellular function
- Abnormal structure
- Independent growth
What are the 4 ways cancer can spread around the body?
Describe local spread
- Malignant tumour invades surround connective tissue
Describe lymphatic spread
- Tumour cells adhere to blood vessels
- Penetrate them and pass to lymph nodes forming a metastasis
Describe blood spread
- Tumour cells invade blood, forms metastasis in secondary tissue
Describe trans-coelomic spread
- Spread across body cavities
- E.g. pleural space, peritoneal
Name the 5 most common metastatic sites
- Adrenal glands
What are the local effects of benign tumours?
What are the local effects of malignant tumours?
- Tissue destruction
- Effects of treatment
What can tissue destruction by malignancy result in