U1 LEC: INTRODUCTION TO HISTOPATH

Question 1

Latin, pathos means?

Answer 1

disease

Question 2

Latin, logos means?

Answer 2

treatise

Question 3

Latin, pathologia

Answer 3

a treatise of disease

Question 4

Greek, pathos means?

Answer 4

suffering

Question 5

Greek, logia means?

Answer 5

study

Question 6

Complete greek word

Answer 6

pathologikos

Question 7

Pathology is also called as?

Answer 7

Pathobiology

Question 8

This is the influence of magic or supernatural.

Answer 8

Anisim

Question 9

This is the deficiency or excess body fluids.

Answer 9

Humors

Question 10

Father of Medicine

Answer 10

Hippocrates

Question 11

This is the postmortems & gross pathology (300BC).

Answer 11

Morbid anatomy

Question 12

He discovered the microscope in 17th century.

Answer 12

Anton van Leewenhoek

Question 13

This is the study of cells

Answer 13

Cellular pathology

Question 14

Father of Pathology

Answer 14

Rudolf Virchow

Question 15

1632 oil painting

Answer 15

The Anatomy Lesson of Dr. Nicolaes Tulp

Question 16

This is the study of the nature, causes, processes, development, consequences of disease and the modifications in cellular function and changes in cellular structure produced in any cell, organ, or part of the body by disease i.e. disease originates at the cellular level.

Answer 16

Pathology (Virchow)

Question 17

This arises from alterations in molecules (genes, proteins, etc.) that influences the survival and behavior of cells.

Answer 17

Cellular disturbance

Question 18

This is the foundation of modern pathology.

Answer 18

Understanding the cellular and molecular abnormalities that give rise to disease.

Question 19

Pathogenesis

Answer 19

pathos (suffering) + genesis (Creation)

Question 20

This refers to the development of disease and the chain of events leading to that disease.

Answer 20

Pathogenesis

Question 21

This refers to the biological mechanism that leads to a diseased state.

Answer 21

Pathogenesis

Question 22

This describes the abnormal condition.

Answer 22

Pathology

Question 23

This explains the physiological processes because of which such condition develops and progresses.

Answer 23

Pathophysiology

Question 24

This refers to the functional changes associated resulting from disease or injury.

Answer 24

Pathophysiology

Question 25

A physician who studies all aspects of disease, on the nature, causes, and development of abnormal conditions, structural and functional changes that result from the process.

Answer 25

Pathologist

Question 26

A physician specialized in the interpretation and diagnoses of the gross, microscopic, and molecular cause by disease in the body.

Answer 26

Pathologist

Question 27

This is the laboratory specialist behind the front-line clinical team.

Answer 27

Pathologist

Question 28

This is a laboratory professional who performs diagnostic analysis on blood, urine, and body fluids.

Answer 28

Medical Technologist (MT)

Question 29

This MT is specialized in histopathologic techniques.

Answer 29

Histotechnologist

Question 30

This is the examination of cells or tissues from a living organism to diagnose disease or to confirm findings of normality.

Answer 30

Biopsy

Question 31

This is routinely biopsied to determine whether they are benign or malignant.

Answer 31

Tumor

Question 32

This is the partial removal of a small portion of tissues to sample only a representation portion of the lesion of interest.

Answer 32

Incision biopsy

Question 33

Forms of incision biopsy

Answer 33

- wedges - cylindrical pieces - cores - punch - scrapings

Question 34

Excision biopsy is also called a?

Answer 34

Wide local incision

Question 35

This involves surgical removal of a tumor and some normal tissue around it.

Answer 35

Excision biopsy

Question 36

This refers to amount of normal tissue taken which depends on the size, histologic type, and thickness of tumor.

Answer 36

Surgical Margin

Question 37

Greek autopsia

Answer 37

to see for oneself

Question 38

Greek autos

Answer 38

oneself

Question 39

Greek opsis

Answer 39

sight, view

Question 40

Other terms for Autopsy

Answer 40

- Post-mortem Examination - Obduction - Necropsy - Autopsia cadaverum

Question 41

This is a thorough examination of a corpse by dissection to determine cause, mode, and manner of death to evaluate any disease or injury.

Answer 41

Autopsy

Question 42

This is the systematic examination of a cadaver for study or for determining the cause of death.

Answer 42

Autopsy

Question 43

Autopsy uses many methodical procedures to determine what?

Answer 43

- etiology and pathogenesis - epidemiology - establishment of genetic causes - family counsel - improvement of safety standards for the living

Question 44

Inaguration of brand new St. John Paul II building

Answer 44

July 4, 2019

Question 45

The Department of Anatomic Pathology consists of the following areas:

Answer 45

- Gross Specimen Examination - Tissue and Slide Processing, Microtomy, Staining - Reception - FNAB room - Frozen and Cytopathology - Fluorescence Microscopy - Immunohistochemistry - Tissue Banking - Slide Archival - Consultant Working Areas - Office of Chairman and CMT - Morgue

Question 46

This room is used for renal and skin biopsies.

Answer 46

Fluorescence Microscopy room

Question 47

FNAB stands for?

Answer 47

Fine Needle Aspiration Biopsy

Question 48

Training Program under Proper receiving of specimens

Answer 48

- Identification - Labeling - Logging /Recording - Fixation

Question 49

Training Program under Assisting in the gross cutting of specimens

Answer 49

- Jots down gross description - Prepares corresponding number tag

Question 50

Training Program under Assist loading of the tissue processor

Answer 50

- Dehydration - Clearing - Paraffin infiltration - Embedding

Question 51

Training Program under Microtomy

Answer 51

- Block Orientation - Rough cutting, soaking, chilling - Ribonning - Floatation - Oven-drying

Question 52

This is used in the Rapid Frozen Section to prepare slide sections for fats, lipids, and immunofluorescence microscopy using unfixed tissues.

Answer 52

Leica CM1860 UV Freezing Microtome

Question 53

Training Program under Staining

Answer 53

- Haematoxylin & Eosin (H&E) - Papanicolau (Pap smear) - Special Stains - Immunohistochemistry

Question 54

Training Program after Staining

Answer 54

- Coverslipping or Slide mounting - Labeling - Reagent and Solution Preparation - Filing of slides and blocks

Question 55

Training Program

Answer 55

1. Proper receiving 2. Assist in gross cutting 3. Assist loading 4. Microtomy 5. Staining 6. Coverslipping/Slide mounting 7. Labeling 8. Reagent and Solution Prep 9. Filing