Unit 22: Cellular Respiration Flashcards

(48 cards)

1
Q

What are the three steps of the ADP-ATP cycle?

A
  1. ATP’s structure
  2. Energy release
  3. Regeneration
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2
Q

What is ATP’s structure?

A

First step of the ADP-ATP cycle. ATP consists of adenine and ribose sugar attached to three phosphate groups. The bonds between these phosphate groups, particularly between the second and third phosphates, store significant energy.

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3
Q

What is energy release?

A

Second step of the ADP-ATP cycle. When a cell needs energy, ATP is converted to ADP (adenosine diphosphate) by cleaving off the terminal phosphate group. This reaction releases energy that can be used for cellular processes.

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4
Q

What is regeneration?

A

Third step of the ADP-ATP cycle. ADP is then “recharged” back to ATP by adding a phosphate group, requiring energy input. This creates a continuous cycle of ATP breakdown and regeneration.

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5
Q

What are three differences between ADP and ATP?

A
  1. Structure- ATP has three phosphate groups, while ADP has only two.
  2. Energy state- ATP is the high-energy form, while ADP is the lower-energy form.
  3. Function- ATP provides energy for cellular processes, while ADP is essentially the “used” form waiting to be recharged.
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6
Q

What are catabolic pathways? (2 things)

A
  1. Involve the breakdown of complex molecules (like fats, carbohydrates, and proteins) into simple molecules.
  2. Often harvest stored chemical energy to produce ATP.
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7
Q

What are anabolic pathways? (2 things).

A
  1. Result in the synthesis of larger molecules from smaller components.
  2. Often use energy in the form of ATP.
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8
Q

What are two examples of molecules that catabolic pathways break down?

A
  1. Fats are broken down into glycerol and fatty acids.
  2. Proteins are broken down into amino acids.
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9
Q

What are four ways in which the products of catabolism are used for anabolic pathways?

A
  1. Citric acid cycle intermediates
  2. Glycolysis intermediates
  3. Through Acetyl-CoA
  4. Through Pyruvate
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10
Q

How are citric acid cycle intermediates used to support anabolic pathways?

A

Can be used to make amino acids.

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11
Q

How is acetyl-CoA used to support anabolic pathways?

A

Used to synthesize fatty acids for phospholipids and fats.

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12
Q

How is pyruvate used to support anabolic pathways?

A

Can be used in gluconeogenesis to make glucose for glycogen or starch.

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13
Q

How are glycolysis intermediates used to support anabolic pathways?

A

Help make nucleotides for DNA/RNA.

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14
Q

What is cellular respiration?

A

Cellular respiration is the process by which cells break down glucose to produce ATP, the energy currency of cells. This process occurs in four interconnected stages.

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15
Q

What are the four interconnected stages of cellular respiration?

A
  1. Glycolysis
  2. Pyruvate processing
  3. Citric acid cycle (Krebs cycle)
  4. Electron transport chain
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16
Q

Where does glycolysis occur?

A

In the cytoplasm of the cell.

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17
Q

What are the four inputs of glycolysis?

A

1 glucose, 2 ATP, 2 NAD⁺, and 2 Pi (inorganic phosphate).

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18
Q

What are the four outputs of glycolysis?

A

2 pyruvate, 2 ATP (4 produced, 2 used), 2 NADH, and 2 H₂O.

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19
Q

What is the net ATP gain from glycolysis?

A

2 ATP

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20
Q

What are the two steps to the overall process of glycolysis?

A
  1. Glucose (6-carbon) is broken down into two 3-carbon pyruvate molecules.
  2. Occurs in two phases: energy investment phase and energy payoff phase.
21
Q

Where does pyruvate processing occur?

A

In the mitochondrial matrix.

22
Q

What are the three inputs of pyruvate processing?

A

2 pyruvate molecules (from glycolysis), 2 NAD⁺, 2 CoA

23
Q

What are the three steps in pyruvate processing?

A

Each pyruvate is converted into acetyl-CoA, producing CO₂ and NAD+ is reduced to NADH.

24
Q

What are the three outputs of pyruvate processing?

A

2 acetyl-CoA, 2 CO₂, and 2 NADH.

25
What is the three step process to pyruvate processing?
1. Each pyruvate is converted to acetyl-CoA 2. CO₂ is released 3. NAD⁺ is reduced to NADH
26
Where does the citric acid cycle occur?
In the mitochondrial matrix.
27
What are the five inputs in the citric acid cycle?
1 acetyl-CoA, 3 NAD⁺, 1 FAD, 1 GDP (or ADP), and 2 H₂O.
28
What is the three step process of the citric acid cycle?
1. Acetyl-CoA is oxidized into two CO2. 2. Moves the acetyl group from acetyl-CoA to oxaloacetate to form citrate. 3. Regeneration of oxaloacetate
29
What are the four total outputs from the citric acid (2 cycles)?
2 ATP, 6 NADH, 2 FADH₂, 4 CO₂
30
Where does the electron transport chain take place?
In the inner mitochondrial membrane.
31
What are the four inputs for the electron transport chain?
1. 10 NADH 2. 2 FADH2 3. O2 4. ADP + Pi
32
What is the three step process of the electron transport chain?
1. Electrons from NADH and FADH₂ pass through a series of electron carriers 2. Energy released pumps H⁺ ions across the inner membrane, creating a proton gradient 3. H⁺ ions flow back through ATP synthase, driving ATP synthesis (chemiosmosis)
33
What are the four outputs of the electron transport chain?
1. NAD⁺ and FAD (recycled) 2. H₂O 3. ATP 4. Approximately 25-32 ATP
34
How many total ATP are produced from one glucose molecule?
29 ATP per glucose is generated from one glucose molecule.
35
What are the roles of NADH and FADH₂ in cellular respiration?
They carry high-energy electrons to the electron transport chain (ETC), where the energy is used to pump protons and drive ATP production.
36
In which stages of cellular respiration are NADH and FADH₂ produced?
Glycolysis, pyruvate processing, and the citric acid cycle.
37
What happens to NADH and FADH₂ in the electron transport chain?
They are oxidized (lose electrons), and the electrons are passed through the ETC to oxygen.
38
Why are NADH and FADH₂ important for ATP production?
Their electrons power the proton gradient that drives ATP synthase during oxidative phosphorylation.
39
What is aerobic respiration?
All eukaryotes and many prokaryotes use oxygen as the final electron acceptor for the ETC.
40
What is anaerobic respiration?
Some prokaryotes use other electron acceptors for the ETC (in poor oxygen environments).
41
How much ATP does aerobic respiration produce per glucose molecule?
About 29 ATP on average.
42
What happens if there's no oxygen available in the cell (no electron acceptor)?
The ETC stops, NADH accumulates, and NAD⁺ runs out, halting glycolysis and other steps.
43
What is the purpose of fermentation?
To regenerate NAD⁺ from NADH so glycolysis can continue to produce a small amount of ATP.
44
How many ATP are produced per glucose in fermentation?
Only 2 ATP (from glycolysis).
45
What happens in lactic acid fermentation?
Pyruvate accepts electrons from NADH, forming lactate and regenerating NAD⁺ (occurs in muscle cells).
46
What two steps happen in alcohol fermentation?
1. Pyruvate is converted to acetaldehyde and CO₂ 2. Acetaldehyde accepts electrons to form ethanol and NAD⁺ (occurs in yeast).
47
Why aerobic respiration is far more efficient than anaerobic respiration?
Aerobic respiration is far more efficient than anaerobic respiration because it produces significantly more ATP per molecule of glucose. Aerobic respiration: 29-32 ATP/glucose. Fermentation: 2 ATP/glucose
48
What is lactic acid fermentation?
When our muscle cells cannot get enough oxygen, they shift to lactic acid fermentation.