Unit 3 Case 2: GIT infection Flashcards
what is crohns
type of inflammatory bowel disease
most commonly occurs in small intestine and colon, can affect part of GIT from mouth to the anus
symptoms of crohns
diarrhoea
abdominal cramps
blood in stool
fissures in the lining of the anus
stricture
fistula
fistula
caused by inflammation
abnormal channel formed between one part of intestine or another
may be between intestine and vagina or bladder
tests used to help diagnose crohns
bloods
stool
endoscopy
colonoscopy
CT and MRIs
tissue scan or biopsy
classifications of drugs that can be used for crohns
anti-inflammatory
immunosuppressors
pain relievers
anti-inflammatory drugs in crohns
corticosteroids such as prednisolone and budesonide
immunosuppressors in crohns
azathiopurine
mercaptopurine
methotrexate
other medications used in crohns treatment
acetaminophen- pain reliever
anti diarrhoeals
other treatments of crohns
nutrition therapy
surgery in more severe cases
amoeba
single-celled eukaryotic organism that changes its shape
moves by pseudopodia
found in water, soil and damp
pseudopodia
temporary projections of the cell
engulf bacteria and other particles as food by phagocytosis
amoebiasis
GI infections that develops when entamoeba histolytica enters intestines
parasite lays eggs that develop into mature cysts and leave through stool
infection is transmitted when you eat or drink something the parasite has contaminated
symptoms of amoebiasis
cramping
diarrhoea
nausea
fever
parasite
organism that lives on/in host organism and gets food from expense of its host
3 main classes
3 main classes of parasites
protozoa
helminths
ectoparasites
protozoa
unicellular
live and multiply inside of your body
transmits through faecal oral route
helminths
multicellular
live in and outside of your body
ectoparasites
multicellular
ticks fleas lice mites that live and feed off your skin
parasitic infections
spread via contaminated food water soil blood equal contact and insect vectors
6 strains of E coli known to cause diarrhoea
shiga toxin producing E coli/verocytotoxin producing e coli/ Enterhohemorrhagic e coli
enteropathogenic e coli
enteroaggressive e coli
enteroinvasive e coli
diffusely adherent e coli
enterotoxigenic E. coli
STEC ETEC EAEC VTEC EHEC EIEC EPIC DAEC
STEC VTEC EHEC
severe food borne disease
severe diarrhoea, stomach cramps, vomiting
can lead to haemolytic ureic syndrome that can cause kidney damage/failre
toxins in intestines from STEC travel into bloodstream and destroy RBCs
EPEC
adheres to intestinal epithelial cells
causes diarrhoea
EAEC
adheres to small and large intestinal epithelia
causes acute and chronic diarrhoea
EIEC
invades colonic epithelial cells
lyses phagosome