Unit 3 Exam Flashcards
(79 cards)
Mutualism
symbiosis that is beneficial to both organisms involved
parasitism
where one organism, the parasite, lives on or inside another organism, the host, causing it some harm
commensalism
an association between two organisms in which one benefits and the other derives neither benefit nor harm.
microbial competition
Populations of microorganisms inhabiting a common environment compete for nutrients and other resources of the environment
contamination
Contamination is the presence of a constituent, impurity
infection
The invasion and growth of germs in the body. The germs may be bacteria, viruses, yeast, fungi, or other microorganisms.
disease
the existence of pathology and an infectious disease is a disease caused by a microorganism
virulence
ability to cause disease
etiology
the cause or causes of a disease
pathogenesis
the process by which an infection leads to disease
opportunistic pathogen
An infection caused by an organism that does not normally cause disease. Opportunistic infections occur in people with weakened immune systems
(How pathogens cause disease) Entrance
portal of entry: sneezing, coughing, urine, blood, bites, lesions. Entrance of pathogen does not mean disease
ID50
dictates if infection and disease will occur, 50: the dose of infection organism required to produce infection in 50% of subjects (infectious dose)
(How pathogens cause disease) Adherence
bacteria use adhesions (virulence factor) sticks/attaches to something
Cranberry juice blocks adhesions (UTI).
(How pathogens cause disease) Colonization
growth of bacteria on the surface. MOST bacteria invade TISSUE NOT CELLS.
phagocyte
eats bacterium
blocking phagocytosis
to remove pathogens and debris through ingestion
MOST BACTERIA
INVASION OF TISSUE DOES NOT EQUAL INVASION OF CELLS (intracellular pathogen)
Disease vs infection
Infection is entrance of pathogen and multiplcation
Disease is damage to host and symptoms, a result of infection
pathogenicity
the capacity of a microbe to cause damage in a host while virulence refers to the degree of damage caused by the microbe
Invasion of tissue by reals of exoenzymes
substances that help bacteria penetrate into tissues:
coagulase
kinases
hyaluronidase: hydrolyzes hyaluronic acid, holds cels together (allows bacteria to go through basement membrane)
collagenase: hydrolyzes collages in connective tissue
invasion of cells
invasions rearrange the host cell cytoskeleton to cradle bacterium into cells
toxin production
enzymes - toxigenicity, many are enzymes exotoxins: soluble proteins secreted into host tissues, most lethal
cytotoxins
hemolysis - lyse a-hemolysin, beta-hemolysin