Unit 4 Topic 1 Flashcards

(49 cards)

1
Q

Capsule

A

outer layer of connective tissue

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2
Q

Cortex

A

outer region containing glomeruli

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3
Q

Medulla

A

inner region containing renal pyramids

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4
Q

Lobe

A

pyramid + associated cortical tissue adjacent

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5
Q

Lobule

A

cortical labyrinth and central medullary ray

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6
Q

Cortical Labyrinth

A

area with glomeruli and closest tubule

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7
Q

Central medullary artery

A

area with only renal tubules

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8
Q

Glomerulus

A

high pressure capillary

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9
Q

Glomerular/Bowman’s capsule

A

structrual support surrounding the glomerulus

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10
Q

Glomerular/Bowman’s Space

A

collects filtrate

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11
Q

What is the sequence of the renal tubule?

A

proximal convoluted tubule–>Nephron Loop–>Collecting Duct

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12
Q

Sequence the Nephron Loop

A

Descending thick–>Descending Thin–>Ascending Thin–>Ascending Thick

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13
Q

What cells line the proximal convoluted tubule?

A

simple columnar epithelium

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14
Q

What cells line the descending thick segment?

A

simple cuboidal epithelium

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15
Q

What cells line the descending thin segment?

A

simple squamous

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16
Q

What cells line the ascending thin segment?

A

simple squamous

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17
Q

What cells line the ascending thick segment?

A

simple cuboidal

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18
Q

What cells line the distal convoluted tubule?

A

simple cuboidal epithelium

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19
Q

What cells line the collecting duct?

A

simple cuboidal epithelium

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20
Q

What makes up 85% of nephrons?

A

cortical nephrons

21
Q

What makes up the majority of nephrons in the cortex?

A

cortical nephrons

22
Q

What makes up 15% of nephrons?

A

juxtamedullary

23
Q

What do the juxtamedullary nephrons dip into?

24
Q

What is the function of the juxtamedullary nephron?

A

concentrates urine

25
What capillaries follow convoluted tubules?
peritubular capillaries
26
What type of capillary is found in the cortex?
peritubular
27
What type of capillary is found primarily in the medulla?
vasa recta
28
What does the vasa recta capillary follow?
nephron loop of juxtamedullary nephrons
29
What are the components of the filtration membrane?
fenestrated epithelium, basal lamina, and podocyte
30
What is the purpose of the fenestrated epithelium?
allows solutes to pass, but not larger cells or large plasma proteins
31
What is the purpose of the basal lamina in the filtration membrane?
repels negatively charged solutes/molecules because it is negatively charged
32
What is the basal lamina of the filtration membrane made out of?
type III collagen
33
What is the purpose of the podocyte in the filtration membrane?
foot processes create slit membranes that prevent filtration of medium-sized proteins
34
What regulates what is released from blood using the filtration membrane?
glomerular filtration
35
What removes substance from the blood and adds back to the tubules?
tubular secretion
36
Does tubular secretion occur along the length of the tubule?
yes
37
What removes substances from the tubules and adds back to the blood?
tubular reabsorbtion
38
Does tubular reabsorbtion occur along the length of the tubule?
yes
39
What is the function of the proximal convoluted tubule?
reabsorbtion
40
What is the difference in the proximal convoluted tubule epithelium and distal convoluted tubule epithelium?
simple columnar in proximal; simple cuboidal in distal
41
What is the function of the distal convoluted tubule
regulates K, Na, and NaCl
42
What is the function of the juxtaglomerular apparatus?
maintains blood pressure and to act as a quality control mechanisim to endure proper glomerular flow rate and efficent sodium reabsorption
43
What is the path of urine once it leaves the collecting duct?
collecting duct-->Ureter-->Bladder
44
What does the descending limb of the nephron loop do to urine?
concentrates urine
45
What does the ascending limb of the nephron loop due to urine?
dilutes urine
46
What limb of the nephron loop is permeable to water and impermeable to solutes?
descending limb
47
What limb of the nephron loop is impermeable to water and permeable to solutes?
ascending limb
48
What removes solutes and water from the nephron loop to maintain the gradient?
vasa recta
49
What is highly sensitive to hormones and uses the gradient?
collecting duct